| Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692-2703, 2007 | 1777 | 2007 |
| Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project JC Lindon, JK Nicholson, E Holmes, H Antti, ME Bollard, H Keun, ... Toxicology and applied pharmacology 187 (3), 137-146, 2003 | 491 | 2003 |
| Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass … ECY Chan, PK Koh, M Mal, PY Cheah, KW Eu, A Backshall, R Cavill, ... Journal of proteome research 8 (1), 352-361, 2009 | 467 | 2009 |
| High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues O Beckonert, M Coen, HC Keun, Y Wang, TMD Ebbels, E Holmes, ... Nature protocols 5 (6), 1019-1032, 2010 | 352 | 2010 |
| The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements JC Lindon, HC Keun, TMD Ebbels, JMT Pearce, E Holmes, JK Nicholson Future Medicine Ltd 6 (7), 691-699, 2005 | 308 | 2005 |
| Analytical reproducibility in 1H NMR-based metabonomic urinalysis HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, G Schlotterbeck, ... Chemical research in toxicology 15 (11), 1380-1386, 2002 | 297 | 2002 |
| Summary recommendations for standardization and reporting of metabolic analyses JC Lindon, JK Nicholson, E Holmes, HC Keun, A Craig, JTM Pearce, ... Nature biotechnology 23 (7), 833-839, 2005 | 272 | 2005 |
| Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA A Kamburov, R Cavill, TMD Ebbels, R Herwig, HC Keun Bioinformatics 27 (20), 2917-2918, 2011 | 259 | 2011 |
| The human early-life exposome (HELIX): project rationale and design M Vrijheid, R Slama, O Robinson, L Chatzi, M Coen, P Van den Hazel, ... Environmental health perspectives 122 (6), 535-544, 2014 | 257 | 2014 |
| Impact of analytical bias in metabonomic studies of human blood serum and plasma O Teahan, S Gamble, E Holmes, J Waxman, JK Nicholson, C Bevan, ... Analytical chemistry 78 (13), 4307-4318, 2006 | 253 | 2006 |
| Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies HC Keun, O Beckonert, JL Griffin, C Richter, D Moskau, JC Lindon, ... Analytical chemistry 74 (17), 4588-4593, 2002 | 229 | 2002 |
| Metabonomic modeling of drug toxicity HC Keun Pharmacology & therapeutics 109 (1-2), 92-106, 2006 | 202 | 2006 |
| Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues Y Wang, ME Bollard, H Keun, H Antti, O Beckonert, TM Ebbels, JC Lindon, ... Analytical biochemistry 323 (1), 26-32, 2003 | 199 | 2003 |
| Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, E Holmes, ... Analytica chimica acta 490 (1-2), 265-276, 2003 | 199 | 2003 |
| Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach TMD Ebbels, HC Keun, OP Beckonert, ME Bollard, JC Lindon, E Holmes, ... Journal of proteome research 6 (11), 4407-4422, 2007 | 193 | 2007 |
| Metabolomics in toxicology and preclinical research T Ramirez, M Daneshian, H Kamp, FY Bois, MR Clench, M Coen, ... Altex 30 (2), 209, 2013 | 173 | 2013 |
| NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches O Beckonert, ME Bollard, TMD Ebbels, HC Keun, H Antti, E Holmes, ... Analytica Chimica Acta 490 (1-2), 3-15, 2003 | 168 | 2003 |
| Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models ME Dumas, SP Wilder, MT Bihoreau, RH Barton, JF Fearnside, K Argoud, ... Nature genetics 39 (5), 666-672, 2007 | 163 | 2007 |
| Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles HC Keun, TMD Ebbels, ME Bollard, O Beckonert, H Antti, E Holmes, ... Chemical research in toxicology 17 (5), 579-587, 2004 | 156 | 2004 |
| Comparative metabonomics of differential hydrazine toxicity in the rat and mouse ME Bollard, HC Keun, O Beckonert, TMD Ebbels, H Antti, AW Nicholls, ... Toxicology and applied pharmacology 204 (2), 135-151, 2005 | 147 | 2005 |
Jeremy K NicholsonPro-Vice Chancellor, Health Sciences; Director, Australian National Phenome Center, MurdochVerified email at murdoch.edu.au
