Thomas Macartney
Thomas Macartney
Molecular Bilologist, University of Dundee
Verified email at dundee.ac.uk
Title
Cited by
Cited by
Year
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
5202012
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
IM Muñoz, K Hain, AC Déclais, M Gardiner, GW Toh, L Sanchez-Pulido, ...
Molecular cell 35 (1), 116-127, 2009
3432009
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
C MacKay, AC Déclais, C Lundin, A Agostinho, AJ Deans, TJ MacArtney, ...
Cell 142 (1), 65-76, 2010
2982010
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
RJ Nichols, N Dzamko, NA Morrice, DG Campbell, M Deak, A Ordureau, ...
Biochemical Journal 430 (3), 393-404, 2010
2812010
The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt …
A Ohta, FR Schumacher, Y Mehellou, C Johnson, A Knebel, TJ Macartney, ...
Biochemical Journal 451 (1), 111-122, 2013
1592013
The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl co-transporters
P De Los Heros, DR Alessi, R Gourlay, DG Campbell, M Deak, ...
Biochemical Journal 458 (3), 559-573, 2014
1302014
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases
D Castor, N Nair, AC Déclais, C Lachaud, R Toth, TJ Macartney, ...
Molecular cell 52 (2), 221-233, 2013
1252013
DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage
EJ Davis, C Lachaud, P Appleton, TJ Macartney, I Näthke, J Rouse
Nature structural & molecular biology 19 (11), 1093, 2012
1252012
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1122015
USP11 augments TGFβ signalling by deubiquitylating ALK5
MA Al-Salihi, L Herhaus, T Macartney, GP Sapkota
Open biology 2 (6), 120063, 2012
962012
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ...
Open biology 4 (3), 130213, 2014
832014
OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3
L Herhaus, M Al-Salihi, T Macartney, S Weidlich, GP Sapkota
Nature communications 4 (1), 1-13, 2013
822013
Identification of the MMS22L-TONSL complex that promotes homologous recombination
E Duro, C Lundin, K Ask, L Sanchez-Pulido, TJ MacArtney, R Toth, ...
Molecular cell 40 (4), 632-644, 2010
792010
The Parkinson's disease VPS35 [D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human
R Mir, F Tonelli, P Lis, T Macartney, NK Polinski, TN Martinez, MY Chou, ...
Biochemical Journal 475 (11), 1861-1883, 2018
552018
Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1
N Zhang, SL Gordon, MJ Fritsch, N Esoof, DG Campbell, R Gourlay, ...
Journal of Neuroscience 35 (6), 2492-2507, 2015
492015
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling
S Strickson, CH Emmerich, ETH Goh, J Zhang, IR Kelsall, T Macartney, ...
Proceedings of the National Academy of Sciences 114 (17), E3481-E3489, 2017
452017
Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia
C Lachaud, D Castor, K Hain, I Muñoz, J Wilson, TJ MacArtney, ...
Journal of cell science 127 (13), 2811-2817, 2014
392014
Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9
A Rojas-Fernandez, L Herhaus, T Macartney, C Lachaud, RT Hay, ...
Scientific reports 5, 9811, 2015
332015
Targeting endogenous proteins for degradation through the affinity-directed protein missile system
LJ Fulcher, LD Hutchinson, TJ Macartney, C Turnbull, GP Sapkota
Open biology 7 (5), 170066, 2017
322017
An affinity-directed protein missile system for targeted proteolysis
LJ Fulcher, T Macartney, P Bozatzi, A Hornberger, A Rojas-Fernandez, ...
Open biology 6 (10), 160255, 2016
322016
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