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Mark A. Eckardt
Mark A. Eckardt
Mass General Brigham / Dana-Farber Cancer Institute
Verified email at mgb.org
Title
Cited by
Cited by
Year
PD-0332991, a Potent and Selective Inhibitor of Cyclin-dependent Kinase 4/6, Demonstrates Inhibition of Proliferation in Renal Cell Carcinoma at Nanomolar Concentrations and …
JE Logan, N Mostofizadeh, AJ Desai, E Von Euw, D Conklin, V Konkankit, ...
Anticancer research 33 (8), 2997-3004, 2013
1122013
Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX …
T Murakami, AS Singh, T Kiyuna, SM Dry, Y Li, AW James, K Igarashi, ...
Oncotarget 7 (30), 47556, 2016
1092016
Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX …
T Murakami, AS Singh, T Kiyuna, SM Dry, Y Li, AW James, K Igarashi, ...
Oncotarget 7 (30), 47556, 2016
1092016
Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient …
K Igarashi, K Kawaguchi, T Kiyuna, K Miyake, M Miyake, S Li, Q Han, ...
Cell Cycle 17 (6), 801-809, 2018
632018
Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of …
K Igarashi, K Kawaguchi, S Li, Q Han, Y Tan, T Murakami, T Kiyuna, ...
Cancer letters 417, 168-173, 2018
572018
Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for …
K Kawaguchi, Q Han, S Li, Y Tan, K Igarashi, T Kiyuna, K Miyake, ...
Cell Cycle 17 (3), 356-361, 2018
532018
Clinical and radiographic outcomes of concentrated bone marrow aspirate with allograft and demineralized bone matrix for posterolateral and interbody lumbar fusion in elderly …
RM Ajiboye, JT Hamamoto, MA Eckardt, JC Wang
European Spine Journal 24, 2567-2572, 2015
482015
Giant cell tumor of bone: are we stratifying results appropriately?
TJ Kremen Jr, NM Bernthal, MA Eckardt, JJ Eckardt
Clinical Orthopaedics and Related Research® 470 (3), 677-683, 2012
452012
Labeling the Stroma of a Patient‐Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft‐Tissue Sarcoma With Red Fluorescent Protein for Rapid Non …
T Kiyuna, T Murakami, Y Tome, K Igarashi, K Kawaguchi, T Russell, ...
Journal of cellular biochemistry 118 (2), 361-365, 2017
412017
The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a …
K Miyake, T Murakami, T Kiyuna, K Igarashi, K Kawaguchi, M Miyake, Y Li, ...
Oncotarget 8 (61), 103129, 2017
392017
Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma
K Igarashi, K Kawaguchi, T Kiyuna, K Miyake, M Miyaki, N Yamamoto, ...
Biochemical and biophysical research communications 506 (4), 912-917, 2018
352018
Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models
K Kawaguchi, Q Han, S Li, Y Tan, K Igarashi, K Miyake, T Kiyuna, ...
Oncotarget 9 (13), 11119, 2018
322018
Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model
K Igarashi, K Kawaguchi, T Kiyuna, K Miyake, M Miyake, Y Li, SD Nelson, ...
Oncotarget 9 (8), 7774, 2018
32*2018
Growth of doxorubicin‐resistant undifferentiated spindle‐cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase
K Igarashi, S Li, Q Han, Y Tan, K Kawaguchi, T Murakami, T Kiyuna, ...
Journal of cellular biochemistry 119 (4), 3537-3544, 2018
312018
Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse …
K Igarashi, K Kawaguchi, T Kiyuna, K Miyake, M Miyake, AS Singh, ...
Biochemical and biophysical research communications 497 (4), 1055-1061, 2018
302018
Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
K Kawaguchi, T Higuchi, S Li, Q Han, Y Tan, K Igarashi, M Zhao, K Miyake, ...
Biochemical and biophysical research communications 503 (4), 3086-3092, 2018
292018
AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
O Kalous, D Conklin, AJ Desai, J Dering, J Goldstein, C Ginther, ...
Breast cancer research and treatment 141, 397-408, 2013
282013
Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model
K Igarashi, K Kawaguchi, S Li, Q Han, Y Tan, E Gainor, T Kiyuna, ...
Oncotarget 9 (27), 19263, 2018
262018
Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children
B Mitton, LL Seeger, MA Eckardt, K Motamedi, FC Eilber, SD Nelson, ...
Journal of pediatric hematology/oncology 36 (5), 337-341, 2014
242014
Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model
K Igarashi, K Kawaguchi, T Kiyuna, K Miyake, M Miyake, Y Li, SD Nelson, ...
Oncotarget 9 (8), 7774, 2018
232018
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