| Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures A Suzuki, T Yamanaka, T Hirose, N Manabe, K Mizuno, M Shimizu, ... The Journal of cell biology 152 (6), 1183-1196, 2001 | 544 | 2001 |
| Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity T Yamanaka, Y Horikoshi, Y Sugiyama, C Ishiyama, A Suzuki, T Hirose, ... Current biology 13 (9), 734-743, 2003 | 429 | 2003 |
| PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex T Yamanaka, Y Horikoshi, A Suzuki, Y Sugiyama, K Kitamura, R Maniwa, ... Genes to Cells 6 (8), 721-731, 2001 | 367 | 2001 |
| aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity A Suzuki, M Hirata, K Kamimura, R Maniwa, T Yamanaka, K Mizuno, ... Current Biology 14 (16), 1425-1435, 2004 | 355 | 2004 |
| Interaction between PAR-3 and the aPKC–PAR-6 complex is indispensable for apical domain development of epithelial cells Y Horikoshi, A Suzuki, T Yamanaka, K Sasaki, K Mizuno, H Sawada, ... Journal of cell science 122 (10), 1595-1606, 2009 | 203 | 2009 |
| Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation T Hirose, Y Izumi, Y Nagashima, Y Tamai-Nagai, H Kurihara, T Sakai, ... Journal of cell science 115 (12), 2485-2495, 2002 | 200 | 2002 |
| Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity T Yamanaka, Y Horikoshi, N Izumi, A Suzuki, K Mizuno, S Ohno Journal of cell science 119 (10), 2107-2118, 2006 | 158 | 2006 |
| Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth T Yamanaka, S Ohno Front Biosci 13 (6), 693-707, 2008 | 146 | 2008 |
| Mutant Huntingtin reduces HSP70 expression through the sequestration of NF‐Y transcription factor T Yamanaka, H Miyazaki, F Oyama, M Kurosawa, C Washizu, H Doi, ... The EMBO journal 27 (6), 827-839, 2008 | 140 | 2008 |
| Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system A Iwata, Y Nagashima, L Matsumoto, T Suzuki, T Yamanaka, H Date, ... Journal of Biological Chemistry 284 (15), 9796-9803, 2009 | 109 | 2009 |
| Atypical protein kinase Cλ binds and regulates p70 S6 kinase K Akimoto, M Nakaya, T Yamanaka, J Tanaka, S MATSUDA, QP WENG, ... Biochemical Journal 335 (2), 417-424, 1998 | 96 | 1998 |
| Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment A Okuzumi, M Kurosawa, T Hatano, M Takanashi, S Nojiri, T Fukuhara, ... Acta Neuropathologica Communications 6, 1-15, 2018 | 75 | 2018 |
| Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division M Yasumi, T Sakisaka, T Hoshino, T Kimura, Y Sakamoto, T Yamanaka, ... Journal of Biological Chemistry 280 (8), 6761-6765, 2005 | 55 | 2005 |
| Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction T Yamanaka, A Tosaki, H Miyazaki, M Kurosawa, Y Furukawa, M Yamada, ... Human molecular genetics 19 (11), 2099-2112, 2010 | 49 | 2010 |
| NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization T Yamanaka, A Tosaki, M Kurosawa, G Matsumoto, M Koike, Y Uchiyama, ... Nature communications 5 (1), 3354, 2014 | 46 | 2014 |
| Intracellular polarity protein PAR‐1 regulates extracellular laminin assembly by regulating the dystroglycan complex M Masuda‐Hirata, A Suzuki, Y Amano, K Yamashita, M Ide, T Yamanaka, ... Genes to cells 14 (7), 835-850, 2009 | 46 | 2009 |
| Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans LA Khan, T Yamanaka, N Nukina Biochemical and biophysical research communications 368 (3), 729-735, 2008 | 24 | 2008 |
| ER dynamics and derangement in neurological diseases T Yamanaka, N Nukina Frontiers in neuroscience 12, 314179, 2018 | 22 | 2018 |
| Proteomics-based approach identifies altered ER domain properties by ALS-linked VAPB mutation T Yamanaka, R Nishiyama, T Shimogori, N Nukina Scientific reports 10 (1), 7610, 2020 | 21 | 2020 |
| Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains T Yamanaka, A Tosaki, M Kurosawa, K Akimoto, T Hirose, S Ohno, ... PloS one 8 (12), e84036, 2013 | 19 | 2013 |
