Primo Schär
Primo Schär
Professor of Molecular Genetics
Verified email at - Homepage
Cited by
Cited by
Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
Y Kubota, RA Nash, A Klungland, P Schär, DE Barnes, T Lindahl
The EMBO journal 15 (23), 6662-6670, 1996
Modification of the human thymine‐DNA glycosylase by ubiquitin‐like proteins facilitates enzymatic turnover
U Hardeland, R Steinacher, J Jiricny, P Schär
The EMBO journal 21 (6), 1456-1464, 2002
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
D Cortázar, C Kunz, J Selfridge, T Lettieri, Y Saito, E MacDougall, A Wirz, ...
Nature 470 (7334), 419-423, 2011
Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination.
YF Wei, P Robins, K Carter, K Caldecott, DJ Pappin, GL Yu, RP Wang, ...
Molecular and Cellular Biology 15 (6), 3206-3216, 1995
DNA glycosylases: in DNA repair and beyond
AL Jacobs, P Schär
Chromosoma 121 (1), 1-20, 2012
NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae
M Valencia, M Bentele, MB Vaze, G Herrmann, E Kraus, SE Lee, P Schär, ...
Nature 414 (6864), 666-669, 2001
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA
T Pfaffeneder, F Spada, M Wagner, C Brandmayr, SK Laube, D Eisen, ...
Nature chemical biology 10 (7), 574-581, 2014
A newly identified DNA ligase of Saccharomyces cerevisiaeinvolved in RAD52-independent repair of DNA double-strand breaks
P Schär, G Herrmann, G Daly, T Lindahl
Genes & Development 11 (15), 1912-1924, 1997
Identification of hMutLβ, a heterodimer of hMLH1 and hPMS1
M Räschle, G Marra, M Nyström-Lahti, P Schär, J Jiricny
Journal of Biological Chemistry 274 (45), 32368-32375, 1999
The enigmatic thymine DNA glycosylase
D Cortázar, C Kunz, Y Saito, R Steinacher, P Schär
DNA repair 6 (4), 489-504, 2007
Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer
K Truninger, M Menigatti, J Luz, A Russell, R Haider, JO Gebbers, ...
Gastroenterology 128 (5), 1160-1171, 2005
Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation
R Steinacher, P Schär
Current biology 15 (7), 616-623, 2005
Saccharomyces cerevisiae LIF1: a function involved in DNA double‐strand break repair related to mammalian XRCC4
G Herrmann, T Lindahl, P Schär
The EMBO Journal 17 (14), 4188-4198, 1998
Arginine methylation regulates DNA polymerase β
N El-Andaloussi, T Valovka, M Toueille, R Steinacher, F Focke, P Gehrig, ...
Molecular cell 22 (1), 51-62, 2006
The versatile thymine DNA‐glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs
U Hardeland, M Bentele, J Jiricny, P SchaÈr
Nucleic acids research 31 (9), 2261-2271, 2003
DNA fragmentation in human fibroblasts under extremely low frequency electromagnetic field exposure
F Focke, D Schuermann, N Kuster, P Schär
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 683 (1 …, 2010
Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil
C Kunz, F Focke, Y Saito, D Schuermann, T Lettieri, J Selfridge, P Schär
PLoS Biol 7 (4), e1000091, 2009
Spontaneous DNA damage, genome instability, and cancer—when DNA replication escapes control
P Schär
Cell 104 (3), 329-332, 2001
Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis
U Hardeland, M Bentele, J Jiricny, P Schär
Journal of biological chemistry 275 (43), 33449-33456, 2000
Recognition of DNA alterations by the mismatch repair system
G MARRA, P Schär
Biochemical Journal 338 (1), 1-13, 1999
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