Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia E Yankova, W Blackaby, M Albertella, J Rak, E De Braekeleer, ... Nature 593 (7860), 597-601, 2021 | 609 | 2021 |
METTL1 promotes let-7 MicroRNA processing via m7G methylation L Pandolfini, I Barbieri, AJ Bannister, A Hendrick, B Andrews, N Webster, ... Molecular Cell 74 (6), 1278-1290. e9, 2019 | 336 | 2019 |
Assembly factors for the membrane arm of human complex I B Andrews, J Carroll, S Ding, IM Fearnley, JE Walker Proceedings of the National Academy of Sciences 110 (47), 18934-18939, 2013 | 158 | 2013 |
A flat BAR protein promotes actin polymerization at the base of clathrin-coated pits L Almeida-Souza, RAW Frank, J García-Nafría, A Colussi, ... Cell 174 (2), 325-337. e14, 2018 | 109 | 2018 |
METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis LV Haute, AG Hendrick, AR D’Souza, CA Powell, P Rebelo-Guiomar, ... Nucleic Acids Research 47 (19), 10267-10281, 2019 | 79 | 2019 |
A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry S Wein, B Andrews, T Sachsenberg, H Santos-Rosa, O Kohlbacher, ... Nature communications 11 (1), 926, 2020 | 67 | 2020 |
Further evidence supporting N7-methylation of guanosine (m7G) in human microRNAs T Kouzarides, L Pandolfini, I Barbieri, AJ Bannister, B Andrews Molecular Cell 79 (2), 201-202, 2020 | 17 | 2020 |
Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances antitumor immunity AA Guirguis, Y Ofir-Rosenfeld, K Knezevic, W Blackaby, D Hardick, ... Cancer Discovery 13 (10), 2228-2247, 2023 | 16 | 2023 |
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit P Rebelo-Guiomar, S Pellegrino, KC Dent, A Sas-Chen, L Miller-Fleming, ... Nature communications 13 (1), 929, 2022 | 15 | 2022 |
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA P Valentini, B Pierattini, E Zacco, D Mangoni, S Espinoza, NA Webster, ... Molecular Therapy-Nucleic Acids 27, 1092-1102, 2022 | 9 | 2022 |
Multidimensional dynamics of the proteome in the neurodegenerative and aging mammalian brain B Andrews, AE Murphy, M Stofella, S Maslen, L Almeida-Souza, ... Molecular & Cellular Proteomics 21 (2), 2022 | 7 | 2022 |
Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages A Bueno-Costa, D Piñeyro, CA García-Prieto, V Ortiz-Barahona, ... Leukemia 36 (8), 2121-2124, 2022 | 6 | 2022 |
Inhibition of n6-methyladenosine (m6a) modification as a novel treatment strategy for alk-positive anaplastic large cell lymphoma (ALCL) L Mun, V Miano, N Webster, B Andrews, N Han, A Burke, I Barberi, ... Leukemia Research 121, S29, 2022 | 1 | 2022 |
Abstract LB171: First-in-class inhibitors of the tRNA methyltransferase METTL1 for the treatment of cancer A Sapetschnig, B Thomas, E Yankova, H Fischl, A Azevedo, S Bucknell, ... Cancer Research 84 (7_Supplement), LB171-LB171, 2024 | | 2024 |
105P Targeting the tRNA methyltransferase METTL1 with small molecule inhibitors in cancer A Sapetschnig, B Thomas, E Yankova, H Fischl, A Azevedo, S Bucknell, ... ESMO Open 9, 2024 | | 2024 |
RNA-Modifying Enzymes and Their Inhibitors WP Blackaby, B Andrews, B Thomas, D Hardick, EA Miska 2020 Medicinal Chemistry Reviews 55, 451-468, 2020 | | 2020 |