Follow
John Maher
John Maher
Chief Scientific Officer, Leucid Bio
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ/CD28 receptor
J Maher, RJ Brentjens, G Gunset, I Rivière, M Sadelain
Nature biotechnology 20 (1), 70-75, 2002
12582002
Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling
S Wilkie, MCI van Schalkwyk, S Hobbs, DM Davies, SJC van der Stegen, ...
Journal of clinical immunology 32, 1059-1070, 2012
5162012
Nucleic acids encoding chimeric T cell receptors
M Sadelain, R Brentjens, J Maher
US Patent 7,446,190, 2008
4492008
Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor
S Wilkie, G Picco, J Foster, DM Davies, S Julien, L Cooper, S Arif, ...
The Journal of Immunology 180 (7), 4901-4909, 2008
4182008
Antibody response to SARS-CoV-2 infection in humans: A systematic review
N Post, D Eddy, C Huntley, MCI Van Schalkwyk, M Shrotri, D Leeman, ...
PloS one 15 (12), e0244126, 2020
3972020
Expression of a chimeric antigen receptor specific for donor HLA class I enhances the potency of human regulatory T cells in preventing human skin transplant rejection
DA Boardman, C Philippeos, GO Fruhwirth, MAA Ibrahim, RF Hannen, ...
American Journal of Transplantation 17 (4), 931-943, 2017
3022017
The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
R Beatson, V Tajadura-Ortega, D Achkova, G Picco, TD Tsourouktsoglou, ...
Nature immunology 17 (11), 1273-1281, 2016
2922016
Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4
S Wilkie, SE Burbridge, L Chiapero-Stanke, ACP Pereira, S Cleary, ...
Journal of Biological Chemistry 285 (33), 25538-25544, 2010
2092010
Strategies to address chimeric antigen receptor tonic signaling
A Ajina, J Maher
Molecular cancer therapeutics 17 (9), 1795-1815, 2018
1842018
CAR T-cells targeting the integrin αvβ6 and co-expressing the chemokine receptor CXCR2 demonstrate enhanced homing and efficacy against several solid malignancies
LM Whilding, L Halim, B Draper, AC Parente-Pereira, T Zabinski, ...
Cancers 11 (5), 674, 2019
1522019
Ovarian cancer immunotherapy using PD‐L1 siRNA targeted delivery from folic acid‐functionalized polyethylenimine: strategies to enhance T cell killing
PY Teo, C Yang, LM Whilding, AC Parente‐Pereira, J Maher, AJT George, ...
Advanced healthcare materials 4 (8), 1180-1189, 2015
1522015
Targeting cytotoxic T lymphocytes for cancer immunotherapy
J Maher, ET Davies
British journal of cancer 91 (5), 817-821, 2004
1522004
CAR T cells targeting the tumor MUC1 glycoprotein reduce triple-negative breast cancer growth
R Zhou, M Yazdanifar, LD Roy, LM Whilding, A Gavrill, J Maher, ...
Frontiers in immunology 10, 1149, 2019
1482019
T cell response to SARS-CoV-2 infection in humans: A systematic review
M Shrotri, MCI van Schalkwyk, N Post, D Eddy, C Huntley, D Leeman, ...
PloS one 16 (1), e0245532, 2021
1362021
Design of a phase I clinical trial to evaluate intratumoral delivery of ErbB-targeted chimeric antigen receptor T-cells in locally advanced or recurrent head and neck cancer
MCI van Schalkwyk, SE Papa, JP Jeannon, TG Urbano, JF Spicer, ...
Human gene therapy clinical development 24 (3), 134-142, 2013
1342013
Trafficking of CAR-engineered human T cells following regional or systemic adoptive transfer in SCID beige mice
AC Parente-Pereira, J Burnet, D Ellison, J Foster, DM Davies, ...
Journal of clinical immunology 31, 710-718, 2011
1332011
Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity?
SJC Van der Stegen, DM Davies, S Wilkie, J Foster, JK Sosabowski, ...
The Journal of Immunology 191 (9), 4589-4598, 2013
1282013
Flexible targeting of ErbB dimers that drive tumorigenesis by using genetically engineered T cells
DM Davies, J Foster, SJC Van Der Stegen, AC Parente-Pereira, ...
Molecular medicine 18, 565-576, 2012
1222012
Enhanced anti-lymphoma activity of CAR19-iNKT cells underpinned by dual CD19 and CD1d targeting
A Rotolo, VS Caputo, M Holubova, N Baxan, O Dubois, MS Chaudhry, ...
Cancer Cell 34 (4), 596-610. e11, 2018
1212018
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer
MY Taher, DM Davies, J Maher
Biochemical Society Transactions 46 (6), 1449-1462, 2018
1182018
The system can't perform the operation now. Try again later.
Articles 1–20