Cytoplasmic chromatin triggers inflammation in senescence and cancer Z Dou, K Ghosh, MG Vizioli, J Zhu, P Sen, KJ Wangensteen, J Simithy, ... Nature 550 (7676), 402-406, 2017 | 1020 | 2017 |
Human laminopathies: nuclei gone genetically awry BC Capell, FS Collins Nature reviews genetics 7 (12), 940-952, 2006 | 617 | 2006 |
Autophagy mediates degradation of nuclear lamina Z Dou, C Xu, G Donahue, T Shimi, JA Pan, J Zhu, A Ivanov, BC Capell, ... Nature 527 (7576), 105-109, 2015 | 605 | 2015 |
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape PP Shah, G Donahue, GL Otte, BC Capell, DM Nelson, K Cao, ... Genes & development 27 (16), 1787-1799, 2013 | 528 | 2013 |
Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome BC Capell, MR Erdos, JP Madigan, JJ Fiordalisi, R Varga, KN Conneely, ... Proceedings of the National Academy of Sciences 102 (36), 12879-12884, 2005 | 456 | 2005 |
A lamin A protein isoform overexpressed in Hutchinson–Gilford progeria syndrome interferes with mitosis in progeria and normal cells K Cao, BC Capell, MR Erdos, K Djabali, FS Collins Proceedings of the National Academy of Sciences 104 (12), 4949-4954, 2007 | 311 | 2007 |
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson–Gilford progeria syndrome R Varga, M Eriksson, MR Erdos, M Olive, I Harten, F Kolodgie, BC Capell, ... Proceedings of the National Academy of Sciences 103 (9), 3250-3255, 2006 | 293 | 2006 |
A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model BC Capell, M Olive, MR Erdos, K Cao, DA Faddah, UL Tavarez, ... Proceedings of the National Academy of Sciences 105 (41), 15902-15907, 2008 | 231 | 2008 |
Mechanisms of cardiovascular disease in accelerated aging syndromes BC Capell, FS Collins, EG Nabel Circulation Research 101 (1), 13-26, 2007 | 152 | 2007 |
Magnetic resonance imaging in quantitative analysis of rotator cuff muscle volume. MJ Tingart, M Apreleva, JT Lehtinen, B Capell, WE Palmer, JJP Warner Clinical Orthopaedics and Related Research (1976-2007) 415, 104-110, 2003 | 147 | 2003 |
MLL1 is essential for the senescence-associated secretory phenotype BC Capell, AM Drake, J Zhu, PP Shah, Z Dou, J Dorsey, DF Simola, ... Genes & development 30 (3), 321-336, 2016 | 145 | 2016 |
The senescence-associated secretory phenotype: critical effector in skin cancer and aging K Ghosh, BC Capell Journal of Investigative Dermatology 136 (11), 2133-2139, 2016 | 140 | 2016 |
CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma AS McNeal, K Liu, V Nakhate, CA Natale, EK Duperret, BC Capell, ... Cancer discovery 5 (10), 1072-1085, 2015 | 106 | 2015 |
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis E Lin-Shiao, Y Lan, M Coradin, A Anderson, G Donahue, CL Simpson, ... Genes & development 32 (2), 181-193, 2018 | 86 | 2018 |
Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect VLRM Verstraeten, LA Peckham, M Olive, BC Capell, FS Collins, ... Proceedings of the National Academy of Sciences 108 (12), 4997-5002, 2011 | 84 | 2011 |
From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging BC Capell, BE Tlougan, SJ Orlow Journal of Investigative Dermatology 129 (10), 2340-2350, 2009 | 63 | 2009 |
LSD1 inhibition promotes epithelial differentiation through derepression of fate-determining transcription factors S Egolf, Y Aubert, M Doepner, A Anderson, A Maldonado-Lopez, ... Cell reports 28 (8), 1981-1992. e7, 2019 | 59 | 2019 |
Human longevity and common variations in the LMNA gene: a meta‐analysis KN Conneely, BC Capell, MR Erdos, P Sebastiani, N Solovieff, AJ Swift, ... Aging cell 11 (3), 475-481, 2012 | 53 | 2012 |
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization S Huang, P Kuri, Y Aubert, M Brewster, N Li, O Farrelly, G Rice, H Bae, ... Cell Stem Cell 28 (9), 1582-1596. e6, 2021 | 52 | 2021 |
Pharmacologic activation of the G protein–coupled estrogen receptor inhibits pancreatic ductal adenocarcinoma CA Natale, J Li, JR Pitarresi, RJ Norgard, T Dentchev, BC Capell, ... Cellular and Molecular Gastroenterology and Hepatology 10 (4), 868-880. e1, 2020 | 45 | 2020 |