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Hamish T J Gilbert
Hamish T J Gilbert
Verified email at manchester.ac.uk
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Year
Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target.
HT Gilbert, N Hodson, P Baird, SM Richardson, JA Hoyland
Scientific Reports 6, 37360, 2016
1292016
Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion
NM Blythe, K Muraki, MJ Ludlow, V Stylianidis, HTJ Gilbert, EL Evans, ...
Journal of Biological Chemistry 294 (46), 17395-17408, 2019
1122019
In situ-forming robust chitosan-poly (ethylene glycol) hydrogels prepared by copper-free azide–alkyne click reaction for tissue engineering
VX Truong, MP Ablett, HTJ Gilbert, J Bowen, SM Richardson, JA Hoyland, ...
Biomaterials Science 2 (2), 167-175, 2014
1022014
The response of human anulus fibrosus cells to cyclic tensile strain is frequency‐dependent and altered with disc degeneration
HTJ Gilbert, JA Hoyland, SJ Millward‐Sadler
Arthritis & Rheumatism 62 (11), 3385-3394, 2010
922010
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading
HTJ Gilbert, V Mallikarjun, O Dobre, MR Jackson, R Pedley, AP Gilmore, ...
Nature communications 10 (1), 4149, 2019
572019
The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with …
HTJ Gilbert, JA Hoyland, AJ Freemont, SJ Millward-Sadler
Arthritis research & therapy 13, 1-12, 2011
522011
Integrin–dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degeneration
HTJ Gilbert, NS Nagra, AJ Freemont, SJ Millward-Sadler, JA Hoyland
PLoS One 8 (9), e72994, 2013
45*2013
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness
A Galarza Torre, JE Shaw, A Wood, HTJ Gilbert, O Dobre, P Genever, ...
Scientific reports 8 (1), 8981, 2018
412018
Integrin–dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degeneration
HTJ Gilbert, NS Nagra, AJ Freemont, SJ Millward-Sadler, JA Hoyland
PLoS One 8 (9), e72994, 2013
392013
Fabrication of 3-dimensional cellular constructs via microstereolithography using a simple, three-component, poly (ethylene glycol) acrylate-based system
SJ Leigh, HTJ Gilbert, IA Barker, JM Becker, SM Richardson, JA Hoyland, ...
Biomacromolecules 14 (1), 186-192, 2013
392013
A microstereolithography resin based on thiol-ene chemistry: towards biocompatible 3D extracellular constructs for tissue engineering
SMRAPD Ian A. Barker a, Matthew P. Ablett b, Hamish T. J. Gilbert b, Simon J ...
Biomaterials Science 2 (4), 472-475, 2014
372014
Stem cell regeneration of degenerated intervertebral discs: current status (update)
HTJ Gilbert, JA Hoyland, SM Richardson
Current pain and headache reports 17, 1-9, 2013
352013
The consequences of ageing, progeroid syndromes and cellular senescence on mechanotransduction and the nucleus
HTJ Gilbert, J Swift
Experimental cell research 378 (1), 98-103, 2019
172019
Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells
NW Hodson, S Patel, SM Richardson, JA Hoyland, HTJ Gilbert
JOR spine 1 (1), e1004, 2018
172018
Regenerative response of degenerate human nucleus pulposus cells to GDF6 stimulation
T Hodgkinson, HTJ Gilbert, T Pandya, AD Diwan, JA Hoyland, ...
International Journal of Molecular Sciences 21 (19), 7143, 2020
112020
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading
HTJ Gilbert, V Mallikarjun, O Dobre, MR Jackson, R Pedley, AP Gilmore, ...
bioRxiv, 317404, 2018
52018
Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human mesenchymal stem cells
J Llewellyn, V Mallikarjun, E Appleton, M Osipova, HTJ Gilbert, ...
Proceedings of the National Academy of Sciences 120 (14), e2210745120, 2023
42023
Stimulation of cardiac fibroblast Piezo1 channels opposes myofibroblast differentiation and induces IL-6 secretion via Ca2+-mediated p38 MAP kinase activation
NM Blythe, V Stylianidis, MJ Ludlow, HTJ Gilbert, EL Evans, ...
BioRxiv, 603456, 2019
42019
Interior decoration: Adapting multiwell plates for high throughput mechanobiology
HTJ Gilbert, J Swift
Biotechnology Journal 10 (10), 1513-1514, 2015
42015
Senescence inhibits the chaperone response to thermal stress
J Llewellyn, V Mallikarjun, E Appleton, M Osipova, HTJ Gilbert, ...
bioRxiv, 2021.06. 15.448532, 2021
32021
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