Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244) JR Dry, S Pavey, CA Pratilas, C Harbron, S Runswick, D Hodgson, ... Cancer research 70 (6), 2264-2273, 2010 | 264 | 2010 |
Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS W Zuidervaart, F Van Nieuwpoort, M Stark, R Dijkman, L Packer, ... British journal of cancer 92 (11), 2032-2038, 2005 | 260 | 2005 |
Nuclear PTEN expression and clinicopathologic features in a population‐based series of primary cutaneous melanoma DC Whiteman, XP Zhou, MC Cummings, S Pavey, NK Hayward, C Eng International journal of cancer 99 (1), 63-67, 2002 | 224 | 2002 |
Microarray expression profiling in melanoma reveals a BRAF mutation signature S Pavey, P Johansson, L Packer, J Taylor, M Stark, PM Pollock, ... Oncogene 23 (23), 4060-4067, 2004 | 209 | 2004 |
Up-regulation of p21WAF1/CIP1 by histone deacetylase inhibitors reduces their cytotoxicity AJ Burgess, S Pavey, R Warrener, LJK Hunter, TJ Piva, EA Musgrove, ... Molecular pharmacology 60 (4), 828-837, 2001 | 186 | 2001 |
Gene expression signature predicts recurrence in lung adenocarcinoma JE Larsen, SJ Pavey, LH Passmore, RV Bowman, NK Hayward, KM Fong Clinical Cancer Research 13 (10), 2946-2954, 2007 | 152 | 2007 |
Expression profiling defines a recurrence signature in lung squamous cell carcinoma JE Larsen, SJ Pavey, LH Passmore, R Bowman, BE Clarke, NK Hayward, ... Carcinogenesis 28 (3), 760-766, 2007 | 142 | 2007 |
Ultraviolet Radiation Induces p16CDKN2A Expression in Human Skin S Pavey, S Conroy, T Russell, B Gabrielli Cancer research 59 (17), 4185-4189, 1999 | 132 | 1999 |
Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR S Goldstone, S Pavey, A Forrest, J Sinnamon, B Gabrielli Oncogene 20 (8), 921-932, 2001 | 115 | 2001 |
Defective cell cycle checkpoints as targets for anti-cancer therapies B Gabrielli, K Brooks, S Pavey Frontiers in pharmacology 3, 9, 2012 | 109 | 2012 |
Expression profiling reveals that methylation of TIMP3 is involved in uveal melanoma development PA Van der Velden, W Zuidervaart, MHMH Hurks, S Pavey, BR Ksander, ... International journal of cancer 106 (4), 472-479, 2003 | 107 | 2003 |
A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress K Brooks, V Oakes, B Edwards, M Ranall, P Leo, S Pavey, A Pinder, ... Oncogene 32 (6), 788-796, 2013 | 102 | 2013 |
G2 phase cell cycle arrest in human skin following UV irradiation S Pavey, T Russell, B Gabrielli Oncogene 20 (43), 6103-6110, 2001 | 100 | 2001 |
Impact of the fibrinolytic enzyme system on prognosis and survival associated with non-small cell lung carcinoma SJ Pavey, GAT Hawson, NA Marsh Blood coagulation & fibrinolysis 12 (1), 51-58, 2001 | 92 | 2001 |
Confirmation of a BRAF mutation‐associated gene expression signature in melanoma P Johansson, S Pavey, N Hayward Pigment cell research 20 (3), 216-221, 2007 | 89 | 2007 |
Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle V Oakes, W Wang, B Harrington, WJ Lee, H Beamish, KM Chia, A Pinder, ... Cell cycle 13 (20), 3302-3311, 2014 | 79 | 2014 |
Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma E Smith, NJ De Young, SJ Pavey, NK Hayward, DJ Nancarrow, ... Molecular cancer 7, 1-12, 2008 | 77 | 2008 |
Loss of p16 expression is associated with histological features of melanoma invasion SJ Pavey, MC Cummings, DC Whiteman, M Castellano, MD Walsh, ... Melanoma research 12 (6), 539-547, 2002 | 73 | 2002 |
Osteopontin is a downstream effector of the PI3-kinase pathway in melanomas that is inversely correlated with functional PTEN L Packer, S Pavey, A Parker, M Stark, P Johansson, B Clarke, P Pollock, ... Carcinogenesis 27 (9), 1778-1786, 2006 | 71 | 2006 |
Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in Cdk4R24C/R24C/TPras Mice E Hacker, HK Muller, N Irwin, B Gabrielli, D Lincoln, S Pavey, MB Powell, ... Cancer research 66 (6), 2946-2952, 2006 | 58 | 2006 |