Marc J Williams
Cited by
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Identification of neutral tumor evolution across cancer types
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
Nature Genetics, 2016
Quantification of subclonal selection in cancer from bulk sequencing data
MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ...
Nature Genetics, 1, 2018
Evolutionary history of human colitis-associated colorectal cancer
AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ...
Gut, gutjnl-2018-316191, 2018
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen …
D Temko, IC Van Gool, E Rayner, M Glaire, S Makino, M Brown, ...
The Journal of pathology, 2018
Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data
K Chkhaidze, T Heide, B Werner, MJ Williams, W Huang, G Caravagna, ...
bioRxiv, 544536, 2019
Reply to ‘Neutral tumor evolution?’
T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ...
Nature genetics 50 (12), 1633, 2018
Measuring Clonal Evolution in Cancer with Genomics
MJ Williams, A Sottoriva, TA Graham
Annual Review of Genomics and Human Genetics 20, 2019
Evolutionary dynamics of neoantigens in growing tumours
E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, ...
bioRxiv, 536433, 2019
Crypt fusion as a homeostatic mechanism in the human colon
AM Baker, C Gabbutt, MJ Williams, B Cereser, N Jawad, ...
Gut, gutjnl-2018-317540, 2019
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios
MJ Williams, L Zapata, B Werner, C Barnes, A Sottoriva, TA Graham
eLife, 661264, 2020
Reply to ‘Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution’
B Werner, MJ Williams, CP Barnes, TA Graham, A Sottoriva
Nature Genetics, 1, 2018
Measuring single cell divisions in human tissues from multi-region sequencing data
B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ...
Nature communications 11 (1), 1-9, 2020
Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’
MJ Williams, B Werner, T Heide, CP Barnes, TA Graham, A Sottoriva
Nature genetics, 1, 2018
Subclonal reconstruction of tumors by using machine learning and population genetics
G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ...
Nature Genetics 52 (9), 898-907, 2020
Model-based tumor subclonal reconstruction
G Caravagna, T Heide, M Williams, L Zapata, D Nichol, K Chkhaidze, ...
bioRxiv, 586560, 2019
Reply: Is the evolution of tumors Darwinian or non-Darwinian?
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
National Science Review, 2018
Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures.
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
Nature genetics 49 (9), 1289, 2017
Functional versus non-functional intratumor heterogeneity in cancer
MJ Williams, B Werner, TA Graham, A Sottoriva
Molecular & Cellular Oncology 3 (4), e1162897, 2016
MLH1 deficiency leads to deregulated mitochondrial metabolism
S Rashid, MO Freitas, D Cucchi, G Bridge, Z Yao, L Gay, M Williams, ...
Cell death & disease 10 (11), 1-11, 2019
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