Trevor M. Lewis
Trevor M. Lewis
Senior Lecturer in Physiology, University of New South Wales
Verified email at - Homepage
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Hyperekplexia associated with compound heterozygote mutations in the β-subunit of the human inhibitory glycine receptor (GLRB)
MI Rees, TM Lewis, JBJ Kwok, GR Mortier, P Govaert, RG Snell, ...
Human molecular genetics 11 (7), 853-860, 2002
Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single‐channel behaviour.
LG Sivilotti, DK McNeil, TM Lewis, MA Nassar, R Schoepfer, D Colquhoun
The Journal of Physiology 500 (1), 123-138, 1997
The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type.
TM Lewis, PC Harkness, LG Sivilotti, D Colquhoun, NS Millar
The Journal of Physiology 505 (Pt 2), 299-306, 1997
Properties of human glycine receptors containing the hyperekplexia mutation α1 (K276E), expressed in Xenopus oocytes
TM Lewis, LG Sivilotti, D Colquhoun, RM Gardiner, R Schoepfer, M Rees
The Journal of physiology 507 (1), 25-40, 1998
Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor
NL Absalom, TM Lewis, W Kaplan, KD Pierce, PR Schofield
Journal of Biological Chemistry 278 (50), 50151-50157, 2003
Compound heterozygosity and nonsense mutations in the α1-subunit of the inhibitory glycine receptor in hyperekplexia
MI Rees, TM Lewis, B Vafa, C Ferrie, P Corry, F Muntoni, H Jungbluth, ...
Human genetics 109 (3), 267-270, 2001
Mechanisms of channel gating of the ligand‐gated ion channel superfamily inferred from protein structure
NL Absalom, TM Lewis, PR Schofield
Experimental physiology 89 (2), 145-153, 2004
Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels
JE Carland, MA Cooper, S Sugiharto, HJ Jeong, TM Lewis, PH Barry, ...
Journal of Biological Chemistry 284 (4), 2023-2030, 2009
Gating mechanisms in Cys-loop receptors
JME Cederholm, PR Schofield, TM Lewis
European Biophysics Journal 39 (1), 37-49, 2009
Kinetic determinants of agonist action at the recombinant human glycine receptor
TM Lewis, PR Schofield, AML McClellan
The Journal of physiology 549 (2), 361-374, 2003
Identification of a new ligand binding domain in the alpha1 subunit of the inhibitory glycine receptor.
B Vafa, TM Lewis, AM Cunningham, P Jacques, JW Lynch, PR Schofield
Journal of neurochemistry 73 (5), 2158-2166, 1999
Pore structure of the Cys-loop ligand-gated ion channels
NL Absalom, PR Schofield, TM Lewis
Neurochemical research 34 (10), 1805-1815, 2009
Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels
S Sugiharto, TM Lewis, AJ Moorhouse, PR Schofield, PH Barry
Biophysical journal 95 (10), 4698-4715, 2008
Immunolabelling for VDAC, the mitochondrial voltage-dependent anion channel, on sarcoplasmic reticulum from amphibian skeletal muscle
TM Lewis, ML Roberts, AH Bretag
Neuroscience letters 181 (1-2), 83-86, 1994
Covalent Trapping of Methyllycaconitine at the α4-α4 Interface of the α4β2 Nicotinic Acetylcholine Receptor ANTAGONIST BINDING SITE AND MODE OF RECEPTOR INHIBITION REVEALED
NL Absalom, G Quek, TM Lewis, T Qudah, I von Arenstorff, JI Ambrus, ...
Journal of Biological Chemistry 288 (37), 26521-26532, 2013
An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology
PH Barry, TM Lewis, AJ Moorhouse
European Biophysics Journal 42 (8), 631-646, 2013
A single P-loop glutamate point mutation to either lysine or arginine switches the cation–anion selectivity of the CNGA2 channel
W Qu, AJ Moorhouse, M Chandra, KD Pierce, TM Lewis, PH Barry
The Journal of general physiology 127 (4), 375-389, 2006
Structure‐Function Relationships of the Human Glycine Receptor: Insights from Hyperekplexia Mutations
TM Lewis, PR Schofield
Annals of the New York Academy of Sciences 868 (1), 681-684, 1999
Mixed antagonistic effects of the ginkgolides at recombinant human ρ< sub> 1</sub> GABA< sub> C</sub> receptors
SH Huang, TM Lewis, SCR Lummis, AJ Thompson, M Chebib, ...
Neuropharmacology 63 (6), 1127-1139, 2012
In vivo somatic delivery of plasmid DNA and retrograde transport to obtain cell‐specific gene expression in the central nervous system
R Morris, BS Morgan, TM Lewis, KD Pierce, A Pisano, PR Schofield
Journal of neurochemistry 90 (6), 1445-1452, 2004
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