| Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase) AM Marinaki, A Ansari, JA Duley, M Arenas, S Sumi, CM Lewis, ... Pharmacogenetics and Genomics 14 (3), 181-187, 2004 | 378 | 2004 |
| Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease A Ansari, C Hassan, J Duley, A Marinaki, EM Shobowale‐Bakre, P Seed, ... Alimentary pharmacology & therapeutics 16 (10), 1743-1750, 2002 | 304 | 2002 |
| Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency S Sumi, AM Marinaki, M Arenas, L Fairbanks, M Shobowale-Bakre, ... Human genetics 111, 360-367, 2002 | 299 | 2002 |
| Uridine and its nucleotides: biological actions, therapeutic potentials GP Connolly, JA Duley Trends in pharmacological sciences 20 (5), 218-225, 1999 | 246 | 1999 |
| Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease A Ansari, M Arenas, SM Greenfield, D Morris, J Lindsay, K Gilshenan, ... Alimentary pharmacology & therapeutics 28 (8), 973-983, 2008 | 213 | 2008 |
| THE IMPORTANCE OF THIOPURINE METHYLTRANSFERASE ACTIVITY FOR THE USE OF AZATHIOPRINE IN TRANSPLANT RECIPIENTS1 PR Chocair, JA Duley, HA Simmonds, JS Cameron Transplantation 53 (5), 1051-1055, 1992 | 200 | 1992 |
| Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy? J Sanderson, A Ansari, T Marinaki, J Duley Annals of clinical biochemistry 41 (4), 294-302, 2004 | 165 | 2004 |
| An international classification of inherited metabolic disorders (ICIMD) CR Ferreira, S Rahman, M Keller, J Zschocke, ICIMD Advisory Group, ... Journal of inherited metabolic disease 44 (1), 164-177, 2021 | 161 | 2021 |
| Low‐dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease A Ansari, N Patel, J Sanderson, J O’donohue, JA Duley, THJ Florin Alimentary pharmacology & therapeutics 31 (6), 640-647, 2010 | 160 | 2010 |
| Long‐term outcome of using allopurinol co‐therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease A Ansari, T Elliott, B Baburajan, P Mayhead, J O’donohue, P Chocair, ... Alimentary pharmacology & therapeutics 28 (6), 734-741, 2008 | 146 | 2008 |
| Nomenclature for alleles of the thiopurine methyltransferase gene ML Appell, J Berg, J Duley, WE Evans, MA Kennedy, L Lennard, ... Pharmacogenetics and genomics 23 (4), 242-248, 2013 | 140 | 2013 |
| Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure ABP van KUILENBURG, D Dobritzsch, R Meinsma, J Haasjes, ... Biochemical journal 364 (1), 157-163, 2002 | 139 | 2002 |
| Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity DPB McGovern, SPL Travis, J Duley, EM Shobowale-Bakre, HR Dalton Gastroenterology 122 (3), 838-839, 2002 | 136 | 2002 |
| Analysis of purines and pyrimidines in blood, urine and other physiological fluids HA Simmonds, JA Duley, PM Davies Techniques in diagnostic human biochemical genetics: a laboratory manual …, 1991 | 136 | 1991 |
| PRPS1 mutations: four distinct syndromes and potential treatment APM de Brouwer, H van Bokhoven, SB Nabuurs, WF Arts, J Christodoulou, ... The American Journal of Human Genetics 86 (4), 506-518, 2010 | 131 | 2010 |
| Thiopurine therapies: problems, complexities, and progress with monitoring thioguanine nucleotides JA Duley, THJ Florin Therapeutic drug monitoring 27 (5), 647-654, 2005 | 122 | 2005 |
| Analysis of human alcohol‐and aldehyde‐metabolizing isozymes by electrophoresis and isoelectric focusing JA Duley, O Harris, RS Holmes Alcoholism: Clinical and Experimental Research 9 (3), 263-271, 1985 | 119 | 1985 |
| Breastmilk-saliva interactions boost innate immunity by regulating the oral microbiome in early infancy SS Al-Shehri, CL Knox, HG Liley, DM Cowley, JR Wright, MG Henman, ... PloS one 10 (9), e0135047, 2015 | 118 | 2015 |
| Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK SA Holme, JA Duley, J Sanderson, PA Routledge, AV Anstey Qjm 95 (7), 439-444, 2002 | 109 | 2002 |
| Novel pharmacogenetic markers for treatment outcome in azathioprine‐treated inflammatory bowel disease MA Smith, AM Marinaki, M Arenas, M Shobowale‐Bakre, CM Lewis, ... Alimentary pharmacology & therapeutics 30 (4), 375-384, 2009 | 104 | 2009 |
