| FSP1 is a glutathione-independent ferroptosis suppressor S Doll, FP Freitas, R Shah, M Aldrovandi, MC da Silva, I Ingold, AG Grocin, ... Nature 575, 693-698, 2019 | 1586 | 2019 |
| Protein myristoylation in health and disease MH Wright, WP Heal, DJ Mann, EW Tate Journal of chemical biology 3, 19-35, 2010 | 290 | 2010 |
| Global profiling of co- and post-translationally N-myristoylated proteomes in human cells E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ... Nature communications 5 (1), 4919, 2014 | 241 | 2014 |
| Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ... Nature chemistry 6 (2), 112-121, 2014 | 218 | 2014 |
| Activity-based probes: discovering new biology and new drug targets WP Heal, THT Dang, EW Tate Chemical Society Reviews 40 (1), 246-257, 2011 | 212 | 2011 |
| N-Myristoyl transferase-mediated protein labelling in vivo WP Heal, SR Wickramasinghe, RJ Leatherbarrow, EW Tate Organic & biomolecular chemistry 6 (13), 2308-2315, 2008 | 169 | 2008 |
| Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides P Thongyoo, N Roqué-Rosell, RJ Leatherbarrow, EW Tate Organic & biomolecular chemistry 6 (8), 1462-1470, 2008 | 165 | 2008 |
| Antibody–PROTAC conjugates enable HER2-dependent targeted protein degradation of BRD4 M Maneiro, N Forte, MM Shchepinova, CS Kounde, V Chudasama, ... ACS chemical biology 15 (6), 1306-1312, 2020 | 158 | 2020 |
| Potent inhibitors of β-tryptase and human leukocyte elastase based on the MCoTI-II scaffold P Thongyoo, C Bonomelli, RJ Leatherbarrow, EW Tate Journal of medicinal chemistry 52 (20), 6197-6200, 2009 | 148 | 2009 |
| Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ... Cell host & microbe 16 (1), 128-140, 2014 | 120 | 2014 |
| Dynamic protein acylation: new substrates, mechanisms, and drug targets T Lanyon-Hogg, M Faronato, RA Serwa, EW Tate Trends in biochemical sciences 42 (7), 566-581, 2017 | 117 | 2017 |
| Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry WP Heal, MH Wright, E Thinon, EW Tate Nature protocols 7 (1), 105-117, 2012 | 116 | 2012 |
| N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis JA Brannigan, BA Smith, Z Yu, AM Brzozowski, MR Hodgkinson, A Maroof, ... Journal of molecular biology 396 (4), 985-999, 2010 | 115 | 2010 |
| Global profiling of protein lipidation using chemical proteomic technologies EW Tate, KA Kalesh, T Lanyon-Hogg, EM Storck, E Thinon Current opinion in chemical biology 24, 48-57, 2015 | 110 | 2015 |
| Multifunctional reagents for quantitative proteome‐wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development M Broncel, RA Serwa, P Ciepla, E Krause, MJ Dallman, AI Magee, ... Angewandte Chemie International Edition 54 (20), 5948-5951, 2015 | 103 | 2015 |
| Bioorthogonal chemical tagging of protein cholesterylation in living cells WP Heal, B Jovanovic, S Bessin, MH Wright, AI Magee, EW Tate Chemical communications 47 (14), 4081-4083, 2011 | 99 | 2011 |
| Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus A Mousnier, AS Bell, DP Swieboda, J Morales-Sanfrutos, I Pérez-Dorado, ... Nature chemistry 10 (6), 599-606, 2018 | 98 | 2018 |
| Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs AS Bell, JE Mills, GP Williams, JA Brannigan, AJ Wilkinson, T Parkinson, ... PLoS neglected tropical diseases 6 (4), e1625, 2012 | 97 | 2012 |
| Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani MH Wright, D Paape, EM Storck, RA Serwa, DF Smith, EW Tate Chemistry & biology 22 (3), 342-354, 2015 | 93 | 2015 |
| Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics EM Storck, J Morales-Sanfrutos, RA Serwa, N Panyain, T Lanyon-Hogg, ... Nature chemistry 11 (6), 552-561, 2019 | 89 | 2019 |
Anthony HolderThe Francis Crick InstituteVerified email at crick.ac.uk
