Richard D Unwin
Richard D Unwin
Research Fellow, the University of Manchester
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Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases
A Pierce, RD Unwin, CA Evans, S Griffiths, L Carney, L Zhang, ...
Molecular & Cellular Proteomics 7 (5), 853-863, 2008
Proteomic changes in renal cancer and co‐ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect
RD Unwin, RA Craven, P Harnden, S Hanrahan, N Totty, M Knowles, ...
PROTEOMICS: International Edition 3 (8), 1620-1632, 2003
Systems-level dynamic analyses of fate change in murine embryonic stem cells
R Lu, F Markowetz, RD Unwin, JT Leek, EM Airoldi, BD MacArthur, ...
Nature 462 (7271), 358-362, 2009
Multiple reaction monitoring to identify sites of protein phosphorylation with high sensitivity
RD Unwin, JR Griffiths, MK Leverentz, A Grallert, IM Hagan, AD Whetton
Molecular & cellular proteomics 4 (8), 1134-1144, 2005
Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS
RD Unwin, JR Griffiths, AD Whetton
Nature protocols 5 (9), 1574, 2010
Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells
RD Unwin, DL Smith, D Blinco, CL Wilson, CJ Miller, CA Evans, ...
Blood 107 (12), 4687-4694, 2006
Quantitative proteomic analysis using isobaric protein tags enables rapid comparison of changes in transcript and protein levels in transformed cells
RD Unwin, A Pierce, RB Watson, DW Sternberg, AD Whetton
Molecular & cellular proteomics 4 (7), 924-935, 2005
A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and …
RD Unwin, JR Griffiths, AD Whetton
Nature protocols 4 (6), 870-877, 2009
Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma
RA Craven, AJ Stanley, S Hanrahan, J Dods, R Unwin, N Totty, ...
Proteomics 6 (9), 2853-2864, 2006
Serological and proteomic evaluation of antibody responses in the identification of tumor antigens in renal cell carcinoma
RD Unwin, P Harnden, D Pappin, D Rahman, P Whelan, RA Craven, ...
Proteomics 3 (1), 45-55, 2003
Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis
AJK Williamson, DL Smith, D Blinco, RD Unwin, S Pearson, C Wilson, ...
Molecular & Cellular Proteomics 7 (3), 459-472, 2008
Relative quantification in proteomics: new approaches for biochemistry
RD Unwin, CA Evans, AD Whetton
Trends in biochemical sciences 31 (8), 473-484, 2006
Peptide quantification using 8-plex isobaric tags and electron transfer dissociation tandem mass spectrometry
D Phanstiel, R Unwin, GC McAlister, JJ Coon
Analytical chemistry 81 (4), 1693-1698, 2009
Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
J Xu, P Begley, SJ Church, S Patassini, KA Hollywood, M Jüllig, MA Curtis, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (6 …, 2016
The potential for proteomic definition of stem cell populations
RD Unwin, SJ Gaskell, CA Evans, AD Whetton
Experimental hematology 31 (12), 1147-1159, 2003
Effects of obesity on perivascular adipose tissue vasorelaxant function: nitric oxide, inflammation and elevated systemic blood pressure
R Aghamohammadzadeh, RD Unwin, AS Greenstein, AM Heagerty
Journal of Vascular Research 52 (5), 299-305, 2015
Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera
TDL Keenan, SJ Clark, RD Unwin, LA Ridge, AJ Day, PN Bishop
Investigative ophthalmology & visual science 53 (12), 7528-7538, 2012
Quantification of proteins by iTRAQ
RD Unwin
LC-MS/MS in Proteomics, 205-215, 2010
Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy
OJ Freeman, RD Unwin, AW Dowsey, P Begley, S Ali, KA Hollywood, ...
Diabetes 65 (1), 228-238, 2016
Systematic proteome and transcriptome analysis of stem cell populations
RD Unwin, AD Whetton
Cell Cycle 5 (15), 1587-1591, 2006
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