|MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures|
T Mondal, S Subhash, R Vaid, S Enroth, S Uday, B Reinius, S Mitra, ...
Nature communications 6, 7743, 2015
|Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity|
A Serrels, T Lund, B Serrels, A Byron, RC McPherson, A von Kriegsheim, ...
Cell 163 (1), 160-173, 2015
|Origins of breast cancer subtypes and therapeutic implications|
AH Sims, A Howell, SJ Howell, RB Clarke
Nature Clinical Practice Oncology 4 (9), 516-525, 2007
|Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer|
D Sproul, C Nestor, J Culley, JH Dickson, JM Dixon, DJ Harrison, ...
Proceedings of the National Academy of Sciences 108 (11), 4364-4369, 2011
|The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets–improving meta-analysis and prediction of prognosis|
AH Sims, GJ Smethurst, Y Hey, MJ Okoniewski, SD Pepper, A Howell, ...
BMC medical genomics 1 (1), 42, 2008
|Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns|
D Sproul, RR Kitchen, CE Nestor, JM Dixon, AH Sims, DJ Harrison, ...
Genome biology 13 (10), 1-16, 2012
|Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers, and therapeutic targets|
L Cassetta, S Fragkogianni, AH Sims, A Swierczak, LM Forrester, ...
Cancer Cell 35 (4), 588-602. e10, 2019
|Wnt pathway activity in breast cancer sub-types and stem-like cells|
R Lamb, MP Ablett, K Spence, G Landberg, AH Sims, RB Clarke
PloS one 8 (7), e67811, 2013
|Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity|
BM Simões, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ...
Cell reports 12 (12), 1968-1977, 2015
|KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals|
S Moleirinho, N Chang, AH Sims, AM Tilston-Lünel, L Angus, A Steele, ...
Oncogene 32 (14), 1821-1830, 2013
|Cyclin D1, Id1 and EMT in breast cancer|
NP Tobin, AH Sims, KL Lundgren, S Lehn, G Landberg
BMC cancer 11 (1), 417, 2011
|Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo|
AH Sims, ME Gent, K Lanthaler, NS Dunn-Coleman, SG Oliver, ...
Applied and environmental microbiology 71 (5), 2737-2747, 2005
|Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue|
CL Wilson, AH Sims, A Howell, CJ Miller, RB Clarke
Endocrine-related cancer 13 (2), 617-628, 2006
|Accurate prediction and validation of response to endocrine therapy in breast cancer|
AK Turnbull, LM Arthur, L Renshaw, AA Larionov, C Kay, AK Dunbier, ...
Journal of Clinical Oncology 33 (20), 2270-2278, 2015
|PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer|
S Loi, S Michiels, J Baselga, JMS Bartlett, SK Singhal, VS Sabine, ...
PloS one 8 (1), e53292, 2013
|A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk|
E Katz, S Dubois-Marshall, AH Sims, D Faratian, J Li, ES Smith, JA Quinn, ...
British journal of cancer 103 (3), 401-410, 2010
|The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers|
ME Rieger, AH Sims, ER Coats, RB Clarke, KJ Briegel
Molecular and cellular biology 30 (17), 4267-4279, 2010
|Use of expressed sequence tag analysis and cDNA microarrays of the filamentous fungus Aspergillus nidulans|
AH Sims, GD Robson, DC Hoyle, SG Oliver, G Turner, RA Prade, ...
Fungal Genetics and Biology 41 (2), 199-212, 2004
|The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells|
B Wang, LE Lindley, V Fernandez-Vega, ME Rieger, AH Sims, KJ Briegel
PloS one 7 (7), e41355, 2012
|Targeting of Rac GTPases blocks the spread of intact human breast cancer|
E Katz, AH Sims, D Sproul, H Caldwell, JM Dixon, RR Meehan, ...
Oncotarget 3 (6), 608, 2012