Andrew H Sims
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Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers, and therapeutic targets
L Cassetta, S Fragkogianni, AH Sims, A Swierczak, LM Forrester, ...
Cancer cell 35 (4), 588-602. e10, 2019
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures
T Mondal, S Subhash, R Vaid, S Enroth, S Uday, B Reinius, S Mitra, ...
Nature communications 6 (1), 7743, 2015
Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity
A Serrels, T Lund, B Serrels, A Byron, RC McPherson, A von Kriegsheim, ...
Cell 163 (1), 160-173, 2015
Origins of breast cancer subtypes and therapeutic implications
AH Sims, A Howell, SJ Howell, RB Clarke
Nature Clinical Practice Oncology 4 (9), 516-525, 2007
Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ...
Cell reports 12 (12), 1968-1977, 2015
The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets–improving meta-analysis and prediction of prognosis
AH Sims, GJ Smethurst, Y Hey, MJ Okoniewski, SD Pepper, A Howell, ...
BMC medical genomics 1, 1-14, 2008
Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns
D Sproul, RR Kitchen, CE Nestor, JM Dixon, AH Sims, DJ Harrison, ...
Genome biology 13 (10), 1-16, 2012
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
D Sproul, C Nestor, J Culley, JH Dickson, JM Dixon, DJ Harrison, ...
Proceedings of the National Academy of Sciences 108 (11), 4364-4369, 2011
MCL-1 is a prognostic indicator and drug target in breast cancer
KJ Campbell, S Dhayade, N Ferrari, AH Sims, E Johnson, SM Mason, ...
Cell death & disease 9 (2), 19, 2018
Immune cell gene signatures for profiling the microenvironment of solid tumors
AJ Nirmal, T Regan, BB Shih, DA Hume, AH Sims, TC Freeman
Cancer immunology research 6 (11), 1388-1400, 2018
Wnt pathway activity in breast cancer sub-types and stem-like cells
R Lamb, MP Ablett, K Spence, G Landberg, AH Sims, RB Clarke
PloS one 8 (7), e67811, 2013
KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals
S Moleirinho, N Chang, AH Sims, AM Tilston-Lünel, L Angus, A Steele, ...
Oncogene 32 (14), 1821-1830, 2013
Cyclin D1, Id1 and EMT in breast cancer
NP Tobin, AH Sims, KL Lundgren, S Lehn, G Landberg
BMC cancer 11, 1-14, 2011
Accurate prediction and validation of response to endocrine therapy in breast cancer
AK Turnbull, LM Arthur, L Renshaw, AA Larionov, C Kay, AK Dunbier, ...
Journal of Clinical Oncology 33 (20), 2270-2278, 2015
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ...
Nature communications 10 (1), 5016, 2019
Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue
CL Wilson, AH Sims, A Howell, CJ Miller, RB Clarke
Endocrine-related cancer 13 (2), 617-628, 2006
The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers
ME Rieger, AH Sims, ER Coats, RB Clarke, KJ Briegel
Molecular and cellular biology 30 (17), 4267-4279, 2010
Transcriptome Analysis of Recombinant Protein Secretion by Aspergillus nidulans and the Unfolded-Protein Response In Vivo
AH Sims, ME Gent, K Lanthaler, NS Dunn-Coleman, SG Oliver, ...
Applied and environmental microbiology 71 (5), 2737-2747, 2005
Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers
C Selli, JM Dixon, AH Sims
Breast Cancer Research 18 (1), 1-10, 2016
PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer
S Loi, S Michiels, J Baselga, JMS Bartlett, SK Singhal, VS Sabine, ...
PloS one 8 (1), e53292, 2013
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