| A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif S Larisch, Y Yi, R Lotan, H Kerner, S Eimerl, W Tony Parks, Y Gottfried, ... Nature cell biology 2 (12), 915-921, 2000 | 332 | 2000 |
| The Sept4 septin locus is required for sperm terminal differentiation in mice H Kissel, MM Georgescu, S Larisch, K Manova, GR Hunnicutt, H Steller Developmental cell 8 (3), 353-364, 2005 | 317 | 2005 |
| The mitochondrial ARTS protein promotes apoptosis through targeting XIAP Y Gottfried, A Rotem, R Lotan, H Steller, S Larisch The EMBO journal 23 (7), 1627-1635, 2004 | 231 | 2004 |
| Characterization of functional domains within Smad4/DPC4 MP de Caestecker, P Hemmati, S Larisch-Bloch, R Ajmera, AB Roberts, ... Journal of Biological Chemistry 272 (21), 13690-13696, 1997 | 211 | 1997 |
| High glucose-induced replicative senescence: point of no return and effect of telomerase S Blazer, E Khankin, Y Segev, R Ofir, M Yalon-Hacohen, Z Kra-Oz, ... Biochemical and biophysical research communications 296 (1), 93-101, 2002 | 124 | 2002 |
| Sept4/ARTS is required for stem cell apoptosis and tumor suppression M García-Fernández, H Kissel, S Brown, T Gorenc, AJ Schile, S Rafii, ... Genes & development 24 (20), 2282-2293, 2010 | 106 | 2010 |
| Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance N Shahar, S Larisch Drug Resistance Updates 52, 100712, 2020 | 103 | 2020 |
| Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients R Elhasid, D Sahar, A Merling, Y Zivony, A Rotem, M Ben-Arush, S Izraeli, ... Oncogene 23 (32), 5468-5475, 2004 | 99 | 2004 |
| Targeting XIAP for promoting cancer cell death—the story of ARTS and SMAC R Abbas, S Larisch Cells 9 (3), 663, 2020 | 93 | 2020 |
| Hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the Fas (CD95/Apo-1) receptor: Fas activation and apoptosis in hypoxic myocytes G Yaniv, M Shilkrut, R Lotan, G Berke, S Larisch, O Binah Cardiovascular research 54 (3), 611-623, 2002 | 93 | 2002 |
| Degradation of Bcl-2 by XIAP and ARTS promotes apoptosis N Edison, Y Curtz, N Paland, D Mamriev, N Chorubczyk, ... Cell reports 21 (2), 442-454, 2017 | 80 | 2017 |
| The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo N Edison, D Zuri, I Maniv, B Bornstein, T Lev, Y Gottfried, S Kemeny, ... Cell Death & Differentiation 19 (2), 356-368, 2012 | 74 | 2012 |
| Ripoptosome: a novel IAP-regulated cell death-signalling platform G Imre, S Larisch, K Rajalingam Journal of molecular cell biology 3 (6), 324-326, 2011 | 55 | 2011 |
| Regulation of the Proapoptotic ARTS Protein by Ubiquitin-mediatedDegradation R Lotan, A Rotem, H Gonen, JPM Finberg, S Kemeny, H Steller, ... Journal of Biological Chemistry 280 (27), 25802-25810, 2005 | 48 | 2005 |
| ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists B Bornstein, Y Gottfried, N Edison, A Shekhtman, T Lev, F Glaser, ... Apoptosis 16, 869-881, 2011 | 47 | 2011 |
| Mitochondrial damage: a target for new therapeutic horizons JF Soustiel, S Larisch Neurotherapeutics 7 (1), 13-21, 2010 | 46 | 2010 |
| Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein S Kemeny, D Dery, Y Loboda, M Rovner, T Lev, D Zuri, JPM Finberg, ... PLoS One 7 (7), e38837, 2012 | 44 | 2012 |
| PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma D Ghannam-Shahbari, E Jacob, RR Kakun, T Wasserman, L Korsensky, ... Oncogene 37 (17), 2213-2224, 2018 | 43 | 2018 |
| Peptides mimicking the unique ARTS-XIAP binding site promote apoptotic cell death in cultured cancer cells N Edison, TH Reingewertz, Y Gottfried, T Lev, D Zuri, I Maniv, MJ Carp, ... Clinical cancer research 18 (9), 2569-2578, 2012 | 38 | 2012 |
| Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration TK Oberoi-Khanuja, C Karreman, S Larisch, UR Rapp, K Rajalingam Journal of Biological Chemistry 287 (34), 28445-28455, 2012 | 37 | 2012 |
