| Azole fungicides–understanding resistance mechanisms in agricultural fungal pathogens CL Price, JE Parker, AGS Warrilow, DE Kelly, SL Kelly Pest management science 71 (8), 1054-1058, 2015 | 292 | 2015 |
| Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, N Rolley, ... Antimicrobial agents and chemotherapy 54 (11), 4527-4533, 2010 | 207 | 2010 |
| Resistance to antifungals that target CYP51 JE Parker, AGS Warrilow, CL Price, JGL Mullins, DE Kelly, SL Kelly Journal of Chemical Biology 7, 143-161, 2014 | 195 | 2014 |
| A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to … CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, DE Kelly, ... Antimicrobial agents and chemotherapy 54 (9), 3578-3583, 2010 | 190 | 2010 |
| Characterization of the sterol 14α‐demethylases of Fusarium graminearum identifies a novel genus‐specific CYP51 function J Fan, M Urban, JE Parker, HC Brewer, SL Kelly, KE Hammond‐Kosack, ... New Phytologist 198 (3), 821-835, 2013 | 180 | 2013 |
| Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens AG Warrilow, JE Parker, DE Kelly, SL Kelly Antimicrobial agents and chemotherapy 57 (3), 1352-1360, 2013 | 166 | 2013 |
| The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme AGS Warrilow, CM Hull, JE Parker, EP Garvey, WJ Hoekstra, WR Moore, ... Antimicrobial agents and chemotherapy 58 (12), 7121-7127, 2014 | 157 | 2014 |
| Impact of recently emerged sterol 14α-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity HJ Cools, JGL Mullins, BA Fraaije, JE Parker, DE Kelly, JA Lucas, ... Applied and environmental microbiology 77 (11), 3830-3837, 2011 | 155 | 2011 |
| Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals J Eddouzi, JE Parker, LA Vale-Silva, A Coste, F Ischer, S Kelly, M Manai, ... Antimicrobial agents and chemotherapy 57 (7), 3182-3193, 2013 | 148 | 2013 |
| Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51) AGS Warrilow, CM Martel, JE Parker, N Melo, DC Lamb, WD Nes, ... Antimicrobial agents and chemotherapy 54 (10), 4235-4245, 2010 | 133 | 2010 |
| Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance … CM Hull, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, DE Kelly, ... Antimicrobial agents and chemotherapy 56 (8), 4223-4232, 2012 | 125 | 2012 |
| Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris JM Rybak, JF Muñoz, KS Barker, JE Parker, BD Esquivel, EL Berkow, ... MBio 11 (3), 10.1128/mbio. 00365-20, 2020 | 120 | 2020 |
| Azole Resistance by Loss of Function of the Sterol Δ5,6-Desaturase Gene (ERG3) in Candida albicans Does Not Necessarily Decrease Virulence LA Vale-Silva, AT Coste, F Ischer, JE Parker, SL Kelly, E Pinto, ... Antimicrobial agents and chemotherapy 56 (4), 1960-1968, 2012 | 113 | 2012 |
| Mechanism of Binding of Prothioconazole to Mycosphaerella graminicola CYP51 Differs from That of Other Azole Antifungals JE Parker, AGS Warrilow, HJ Cools, CM Martel, WD Nes, BA Fraaije, ... Applied and environmental microbiology 77 (4), 1460-1465, 2011 | 109 | 2011 |
| Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-α Demethylase (CYP51) Isoenzymes A and B AGS Warrilow, N Melo, CM Martel, JE Parker, WD Nes, SL Kelly, DE Kelly Antimicrobial agents and chemotherapy 54 (10), 4225-4234, 2010 | 108 | 2010 |
| Heterologous Expression of Mutated Eburicol 14α-Demethylase (CYP51) Proteins of Mycosphaerella graminicola To Assess Effects on Azole Fungicide Sensitivity … HJ Cools, JE Parker, DE Kelly, JA Lucas, BA Fraaije, SL Kelly Applied and Environmental Microbiology 76 (9), 2866-2872, 2010 | 107 | 2010 |
| The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus T Furukawa, N Van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, ... Nature communications 11 (1), 427, 2020 | 106 | 2020 |
| Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola JGL Mullins, JE Parker, HJ Cools, RC Togawa, JA Lucas, BA Fraaije, ... PloS one 6 (6), e20973, 2011 | 104 | 2011 |
| Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2 CM Hull, O Bader, JE Parker, M Weig, U Gross, AGS Warrilow, DE Kelly, ... Antimicrobial agents and chemotherapy 56 (12), 6417-6421, 2012 | 96 | 2012 |
| Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-α-demethylase JE Parker, AGS Warrilow, HJ Cools, BA Fraaije, JA Lucas, K Rigdova, ... Applied and environmental microbiology 79 (5), 1639-1645, 2013 | 94 | 2013 |
Bart FraaijeBusiness Unit Biointeractions & Plant Health, Wageningen University & ResearchVerified email at wur.nl
