Todd Hyster
Todd Hyster
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Biotinylated Rh (III) complexes in engineered streptavidin for accelerated asymmetric C–H activation
TK Hyster, L Knörr, TR Ward, T Rovis
Science 338 (6106), 500-503, 2012
Rhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C− H/N− H activation
TK Hyster, T Rovis
Journal of the American Chemical Society 132 (30), 10565-10569, 2010
A coupling of benzamides and donor/acceptor diazo compounds to form γ-lactams via Rh (III)-catalyzed C–H activation
TK Hyster, KE Ruhl, T Rovis
Journal of the American Chemical Society 135 (14), 5364-5367, 2013
Pyridine synthesis from oximes and alkynes via rhodium (III) catalysis: Cp* and Cp t provide complementary selectivity
TK Hyster, T Rovis
Chemical communications 47 (43), 11846-11848, 2011
Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light
MA Emmanuel, NR Greenberg, DG Oblinsky, TK Hyster
Nature 540 (7633), 414-417, 2016
Photoexcitation of flavoenzymes enables a stereoselective radical cyclization
KF Biegasiewicz, SJ Cooper, X Gao, DG Oblinsky, JH Kim, SE Garfinkle, ...
Science 364 (6446), 1166-1169, 2019
An improved catalyst architecture for rhodium (III) catalyzed C–H activation and its application to pyridone synthesis
TK Hyster, T Rovis
Chemical science 2 (8), 1606-1610, 2011
Enantioselective enzyme-catalyzed aziridination enabled by active-site evolution of a cytochrome P450
CC Farwell, RK Zhang, JA McIntosh, TK Hyster, FH Arnold
ACS central science 1 (2), 89-93, 2015
Enzyme-controlled nitrogen-atom transfer enables regiodivergent C–H amination
TK Hyster, CC Farwell, AR Buller, JA McIntosh, FH Arnold
Journal of the American Chemical Society 136 (44), 15505-15508, 2014
Rhodium (III)-catalyzed oxidative carbonylation of benzamides with carbon monoxide
Y Du, TK Hyster, T Rovis
Chemical communications 47 (44), 12074-12076, 2011
Rh (III)-Catalyzed Intramolecular Hydroarylation, Amidoarylation, and Heck-type Reaction: Three Distinct Pathways Determined by Amide Directing Group
TA Davis, TK Hyster, T Rovis
Angewandte Chemie (International ed. in English) 52 (52), 14181, 2013
Genetic optimization of metalloenzymes: enhancing enzymes for non‐natural reactions
TK Hyster, TR Ward
Angewandte Chemie International Edition 55 (26), 7344-7357, 2016
Chemoselectivity in Catalytic C C and C H Bond Activation: Controlling Intermolecular Carboacylation and Hydroarylation of Alkenes
MT Wentzel, VJ Reddy, TK Hyster, CJ Douglas
Angewandte Chemie 121 (33), 6237-6239, 2009
Enantioselective imidation of sulfides via enzyme-catalyzed intermolecular nitrogen-atom transfer
CC Farwell, JA McIntosh, TK Hyster, ZJ Wang, FH Arnold
Journal of the American Chemical Society 136 (24), 8766-8771, 2014
Ligand design for Rh (III)-catalyzed C–H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones
TK Hyster, DM Dalton, T Rovis
Chemical science 6 (1), 254-258, 2015
Catalytic promiscuity enabled by photoredox catalysis in nicotinamide-dependent oxidoreductases
KF Biegasiewicz, SJ Cooper, MA Emmanuel, DC Miller, TK Hyster
Nature chemistry 10 (7), 770-775, 2018
Asymmetric redox-neutral radical cyclization catalysed by flavin-dependent ‘ene’-reductases
MJ Black, KF Biegasiewicz, AJ Meichan, DG Oblinsky, B Kudisch, ...
Nature chemistry 12 (1), 71-75, 2020
Enantioselective hydrogen atom transfer: discovery of catalytic promiscuity in flavin-dependent ‘ene’-reductases
BA Sandoval, AJ Meichan, TK Hyster
Journal of the American Chemical Society 139 (33), 11313-11316, 2017
Emerging strategies for expanding the toolbox of enzymes in biocatalysis
BA Sandoval, TK Hyster
Current Opinion in Chemical Biology 55, 45-51, 2020
Photoenzymatic catalysis enables radical‐mediated ketone reduction in ene‐reductases
BA Sandoval, SI Kurtoic, MM Chung, KF Biegasiewicz, TK Hyster
Angewandte Chemie 131 (26), 8806-8810, 2019
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