| ATF6 decreases myocardial ischemia/reperfusion damage and links ER stress and oxidative stress signaling pathways in the heart JK Jin, EA Blackwood, K Azizi, DJ Thuerauf, AG Fahem, C Hofmann, ... Circulation research 120 (5), 862-875, 2017 | 266 | 2017 |
| Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis EA Blackwood, K Azizi, DJ Thuerauf, RJ Paxman, L Plate, JW Kelly, ... Nature communications 10 (1), 187, 2019 | 159 | 2019 |
| Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins R Paxman, L Plate, EA Blackwood, C Glembotski, ET Powers, ... Elife 7, e37168, 2018 | 98 | 2018 |
| ATF6 regulates cardiac hypertrophy by transcriptional induction of the mTORC1 activator, Rheb EA Blackwood, C Hofmann, M Santo Domingo, AS Bilal, A Sarakki, ... Circulation research 124 (1), 79-93, 2019 | 92 | 2019 |
| CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α CBB Gray, T Suetomi, S Xiang, S Mishra, EA Blackwood, CC Glembotski, ... Journal of molecular and cellular cardiology 103, 48-55, 2017 | 73 | 2017 |
| ER protein quality control and the unfolded protein response in the heart A Arrieta, EA Blackwood, CC Glembotski Coordinating Organismal Physiology Through the Unfolded Protein Response …, 2018 | 40 | 2018 |
| Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart A Arrieta, EA Blackwood, WT Stauffer, M Santo Domingo, AS Bilal, ... Journal of Biological Chemistry 295 (22), 7566-7583, 2020 | 34 | 2020 |
| ATF6 as a Nodal Regulator of Proteostasis in the Heart CC Glembotski, A Arrieta, EA Blackwood, WT Stauffer Frontiers in physiology 11, 527299, 2020 | 29 | 2020 |
| The ER unfolded protein response effector, ATF6, reduces cardiac fibrosis and decreases activation of cardiac fibroblasts WT Stauffer, EA Blackwood, K Azizi, RJ Kaufman, CC Glembotski International journal of molecular sciences 21 (4), 1373, 2020 | 24 | 2020 |
| Integrating ER and mitochondrial proteostasis in the healthy and diseased heart A Arrieta, EA Blackwood, WT Stauffer, CC Glembotski Frontiers in Cardiovascular Medicine 6, 193, 2020 | 22 | 2020 |
| Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response EA Blackwood, DJ Thuerauf, M Stastna, H Stephens, Z Sand, A Pentoney, ... Journal of molecular and cellular cardiology 143, 132-144, 2020 | 17 | 2020 |
| Dietary choline intake is necessary to prevent systems‐wide organ pathology and reduce Alzheimer's disease hallmarks N Dave, JM Judd, A Decker, W Winslow, P Sarette, O Villarreal Espinosa, ... Aging Cell 22 (2), e13775, 2023 | 15 | 2023 |
| Designing novel therapies to mend broken hearts: ATF6 and cardiac proteostasis EA Blackwood, AS Bilal, WT Stauffer, A Arrieta, CC Glembotski Cells 9 (3), 602, 2020 | 12 | 2020 |
| The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes KG Marsh, A Arrieta, DJ Thuerauf, EA Blackwood, L MacDonnell, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (5 …, 2021 | 10 | 2021 |
| Sledgehammer to scalpel: broad challenges to the heart and other tissues yield specific cellular responses via transcriptional regulation of the ER-stress master regulator ATF6α WT Stauffer, A Arrieta, EA Blackwood, CC Glembotski International Journal of Molecular Sciences 21 (3), 1134, 2020 | 9 | 2020 |
| Unfolding the roles of mitochondria as therapeutic targets for heart disease CC Glembotski, A Arrieta, EA Blackwood Journal of the American College of Cardiology 73 (14), 1807-1810, 2019 | 8 | 2019 |
| Reactive oxygen species (ROS)-Activatable prodrug for selective activation of ATF6 after ischemia/reperfusion injury JE Palmer, BM Brietske, TC Bate, EA Blackwood, M Garg, CC Glembotski, ... ACS Medicinal Chemistry Letters 11 (3), 292-297, 2019 | 7 | 2019 |
| University of Arizona EA Blackwood United States, 0 | 7 | |
| Simultaneous isolation and culture of atrial myocytes, ventricular myocytes, and non-myocytes from an adult mouse heart EA Blackwood, AS Bilal, K Azizi, A Sarakki, CC Glembotski JoVE (Journal of Visualized Experiments), e61224, 2020 | 6 | 2020 |
| Optimizing Adeno-Associated Virus Serotype 9 for Studies of Cardiac Chamber–Specific Gene Regulation AS Bilal, EA Blackwood, DJ Thuerauf, CC Glembotski Circulation 143 (20), 2025-2027, 2021 | 5 | 2021 |
