Follow
Maria Spies
Maria Spies
University of Iowa, Department of Biochemistry and Molecular Biology
Verified email at uiowa.edu
Title
Cited by
Cited by
Year
RecBCD enzyme is a bipolar DNA helicase
MS Dillingham, M Spies, SC Kowalczykowski
Nature 423 (6942), 893-897, 2003
2762003
A molecular throttle: the recombination hotspot χ controls DNA translocation by the RecBCD helicase
M Spies, PR Bianco, MS Dillingham, N Handa, RJ Baskin, ...
Cell 114 (5), 647-654, 2003
2052003
Mismatch repair during homologous and homeologous recombination
M Spies, R Fishel
Cold Spring Harbor perspectives in biology 7 (3), a022657, 2015
1732015
Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52–ssDNA complexes
JM Grimme, M Honda, R Wright, Y Okuno, E Rothenberg, AV Mazin, T Ha, ...
Nucleic acids research 38 (9), 2917-2930, 2010
1732010
RecBCD enzyme switches lead motor subunits in response to χ recognition
M Spies, I Amitani, RJ Baskin, SC Kowalczykowski
Cell 131 (4), 694-705, 2007
1472007
Small-molecule inhibitors targeting DNA repair and DNA repair deficiency in research and cancer therapy
SR Hengel, MA Spies, M Spies
Cell chemical biology 24 (9), 1101-1119, 2017
1422017
Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes
E Rothenberg, JM Grimme, M Spies, T Ha
Proceedings of the National Academy of Sciences 105 (51), 20274-20279, 2008
1242008
A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA
LA Yates, RJ Aramayo, N Pokhrel, CC Caldwell, JA Kaplan, RL Perera, ...
Nature communications 9 (1), 5447, 2018
1212018
The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double …
RA Pugh, M Honda, H Leesley, A Thomas, Y Lin, MJ Nilges, IKO Cann, ...
Journal of biological chemistry 283 (3), 1732-1743, 2008
1192008
The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins
M Spies, SC Kowalczykowski
Molecular cell 21 (4), 573-580, 2006
1172006
Homologous recombination by the RecBCD and RecF pathways
M Spies, SC Kowalczykowski
The bacterial chromosome, 389-403, 2004
982004
G-quadruplex recognition and remodeling by the FANCJ helicase
CG Wu, M Spies
Nucleic acids research 44 (18), 8742-8753, 2016
962016
Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase
M Honda, J Park, RA Pugh, T Ha, M Spies
Molecular cell 35 (5), 694-703, 2009
932009
Dynamics and selective remodeling of the DNA-binding domains of RPA
N Pokhrel, CC Caldwell, EI Corless, EA Tillison, J Tibbs, N Jocic, ...
Nature structural & molecular biology 26 (2), 129-136, 2019
922019
Dynamic binding of replication protein a is required for DNA repair
R Chen, S Subramanyam, AH Elcock, M Spies, MS Wold
Nucleic acids research 44 (12), 5758-5772, 2016
922016
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
E Malacaria, GM Pugliese, M Honda, V Marabitti, FA Aiello, M Spies, ...
Nature communications 10 (1), 1412, 2019
902019
Sequence-dependent base pair stepping dynamics in XPD helicase unwinding
Z Qi, RA Pugh, M Spies, YR Chemla
eLife 2, 2013
892013
Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function
I Murfuni, G Basile, S Subramanyam, E Malacaria, M Bignami, M Spies, ...
PLoS genetics 9 (10), e1003910, 2013
852013
Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
SR Hengel, E Malacaria, L Folly da Silva Constantino, FE Bain, A Diaz, ...
Elife 5, e14740, 2016
832016
Tyrosine phosphorylation enhances RAD52‐mediated annealing by modulating its DNA binding
M Honda, Y Okuno, J Yoo, T Ha, M Spies
The EMBO journal 30 (16), 3368-3382, 2011
762011
The system can't perform the operation now. Try again later.
Articles 1–20