| Physiologically based pharmacokinetic modeling in drug discovery and development: a pharmaceutical industry perspective HM Jones, Y Chen, C Gibson, T Heimbach, N Parrott, SA Peters, ... Clinical Pharmacology & Therapeutics 97 (3), 247-262, 2015 | 456 | 2015 |
| A novel strategy for physiologically based predictions of human pharmacokinetics HM Jones, N Parrott, K Jorga, T Lavé Clinical pharmacokinetics 45, 511-542, 2006 | 390 | 2006 |
| A novel strategy for physiologically based predictions of human pharmacokinetics HM Jones, N Parrott, K Jorga, T Lavé Clinical pharmacokinetics 45, 511-542, 2006 | 390 | 2006 |
| The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group M Koziolek, S Alcaro, P Augustijns, AW Basit, M Grimm, B Hens, CL Hoad, ... European Journal of Pharmaceutical Sciences 134, 31-59, 2019 | 299 | 2019 |
| Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review M Vertzoni, P Augustijns, M Grimm, M Koziolek, G Lemmens, N Parrott, ... European journal of pharmaceutical sciences 134, 153-175, 2019 | 193 | 2019 |
| Prediction of intestinal absorption: comparative assessment of gastroplus™ and idea™ N Parrott, T Lavé European journal of pharmaceutical sciences 17 (1-2), 51-61, 2002 | 187 | 2002 |
| Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review C Stillhart, K Vučićević, P Augustijns, AW Basit, H Batchelor, TR Flanagan, ... European Journal of Pharmaceutical Sciences 147, 105280, 2020 | 181 | 2020 |
| Predicting pharmacokinetics of drugs using physiologically based modeling—application to food effects N Parrott, V Lukacova, G Fraczkiewicz, MB Bolger The AAPS journal 11, 45-53, 2009 | 163 | 2009 |
| Predicting pharmacokinetic food effects using biorelevant solubility media and physiologically based modelling HM Jones, N Parrott, G Ohlenbusch, T Lavé Clinical pharmacokinetics 45, 1213-1226, 2006 | 161 | 2006 |
| Applications of physiologically based absorption models in drug discovery and development N Parrott, T Lave Molecular Pharmaceutics 5 (5), 760-775, 2008 | 132 | 2008 |
| A novel orally available small molecule that inhibits hepatitis B virus expression H Mueller, S Wildum, S Luangsay, J Walther, A Lopez, P Tropberger, ... Journal of hepatology 68 (3), 412-420, 2018 | 131 | 2018 |
| CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor L Lindemann, G Jaeschke, A Michalon, E Vieira, M Honer, W Spooren, ... Journal of Pharmacology and Experimental Therapeutics 339 (2), 474-486, 2011 | 127 | 2011 |
| Development of a physiologically based model for oseltamivir and simulation of pharmacokinetics in neonates and infants N Parrott, B Davies, G Hoffmann, A Koerner, T Lave, E Prinssen, ... Clinical pharmacokinetics 50, 613-623, 2011 | 121 | 2011 |
| Challenges and opportunities with modelling and simulation in drug discovery and drug development T Lavé, N Parrott, HP Grimm, A Fleury, M Reddy Xenobiotica 37 (10-11), 1295-1310, 2007 | 119 | 2007 |
| A strategy for preclinical formulation development using GastroPlus™ as pharmacokinetic simulation tool and a statistical screening design applied to a dog study M Kuentz, S Nick, N Parrott, D Röthlisberger European journal of pharmaceutical sciences 27 (1), 91-99, 2006 | 119 | 2006 |
| An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery N Parrott, N Paquereau, P Coassolo, T Lavé Journal of pharmaceutical sciences 94 (10), 2327-2343, 2005 | 115 | 2005 |
| Physiologically based pharmacokinetic modelling for first-in-human predictions: an updated model building strategy illustrated with challenging industry case studies NA Miller, MB Reddy, AT Heikkinen, V Lukacova, N Parrott Clinical pharmacokinetics 58, 727-746, 2019 | 112 | 2019 |
| Application of full physiological models for pharmaceutical drug candidate selection and extrapolation of pharmacokinetics to man N Parrott, H Jones, N Paquereau, T Lavé Basic & clinical pharmacology & toxicology 96 (3), 193-199, 2005 | 105 | 2005 |
| Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network Z Vinarov, B Abrahamsson, P Artursson, H Batchelor, P Berben, ... Advanced Drug Delivery Reviews 171, 289-331, 2021 | 98 | 2021 |
| Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches Y Guo, X Chu, NJ Parrott, KLR Brouwer, V Hsu, S Nagar, P Matsson, ... Clinical Pharmacology & Therapeutics 104 (5), 865-889, 2018 | 98 | 2018 |
Thierry LaveVerified email at roche.com
