| Exercise promotes healthy aging of skeletal muscle GD Cartee, RT Hepple, MM Bamman, JR Zierath Cell metabolism 23 (6), 1034-1047, 2016 | 507 | 2016 |
| Understanding the cellular and molecular mechanisms of physical activity-induced health benefits PD Neufer, MM Bamman, DM Muoio, C Bouchard, DM Cooper, ... Cell metabolism 22 (1), 4-11, 2015 | 489 | 2015 |
| Innervation and neuromuscular control in ageing skeletal muscle RT Hepple, CL Rice The Journal of physiology 594 (8), 1965-1978, 2016 | 362 | 2016 |
| Mitochondrial structure and function are disrupted by standard isolation methods M Picard, T Taivassalo, D Ritchie, KJ Wright, MM Thomas, C Romestaing, ... PloS one 6 (3), e18317, 2011 | 360 | 2011 |
| Mitochondria: isolation, structure and function M Picard, T Taivassalo, G Gouspillou, RT Hepple The Journal of physiology 589 (18), 4413-4421, 2011 | 285 | 2011 |
| Resistance and aerobic training in older men: effects onV˙o2 peak and the capillary supply to skeletal muscle RT Hepple, SLM Mackinnon, JM Goodman, SG Thomas, MJ Plyley Journal of applied physiology 82 (4), 1305-1310, 1997 | 280 | 1997 |
| Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle SL Rowan, K Rygiel, FM Purves-Smith, NM Solbak, DM Turnbull, ... PloS one 7 (1), e29082, 2012 | 273 | 2012 |
| Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers M Picard, D Ritchie, KJ Wright, C Romestaing, MM Thomas, SL Rowan, ... Aging cell 9 (6), 1032-1046, 2010 | 239 | 2010 |
| Determinants of VO2 max decline with aging: an integrated perspective AC Betik, RT Hepple Applied physiology, nutrition, and metabolism 33 (1), 130-140, 2008 | 234 | 2008 |
| Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal function M Picard, RT Hepple, Y Burelle American Journal of Physiology-Cell Physiology 302 (4), C629-C641, 2012 | 225 | 2012 |
| Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans G Gouspillou, N Sgarioto, S Kapchinsky, F Purves‐Smith, B Norris, ... The FASEB Journal 28 (4), 1621-1633, 2014 | 198 | 2014 |
| Alterations in intrinsic mitochondrial function with aging are fiber type‐specific and do not explain differential atrophy between muscles M Picard, D Ritchie, MM Thomas, KJ Wright, RT Hepple Aging cell 10 (6), 1047-1055, 2011 | 158 | 2011 |
| Mitochondrial involvement and impact in aging skeletal muscle RT Hepple Frontiers in aging neuroscience 6, 211, 2014 | 156 | 2014 |
| Fiber typing in aging muscle FM Purves-Smith, N Sgarioto, RT Hepple Exercise and sport sciences reviews 42 (2), 45-52, 2014 | 136 | 2014 |
| The impact of ageing, physical activity, and pre‐frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men F St‐Jean‐Pelletier, CH Pion, JP Leduc‐Gaudet, N Sgarioto, I Zovilé, ... Journal of cachexia, sarcopenia and muscle 8 (2), 213-228, 2017 | 133 | 2017 |
| The relationship between muscle fiber type-specific PGC-1α content and mitochondrial content varies between rodent models and humans G Gouspillou, N Sgarioto, B Norris, S Barbat-Artigas, ... PloS one 9 (8), e103044, 2014 | 129 | 2014 |
| Structural basis of muscle O2 diffusing capacity: evidence from muscle function in situ RT Hepple, MC Hogan, C Stary, DE Bebout, O Mathieu-Costello, ... Journal of Applied Physiology 88 (2), 560-566, 2000 | 129 | 2000 |
| Skeletal Muscle Aging in F344BN F1-Hybrid Rats: I. Mitochondrial Dysfunction Contributes to the Age-Associated Reduction in VO2max JL Hagen, DJ Krause, DJ Baker, MH Fu, MA Tarnopolsky, RT Hepple The Journals of Gerontology Series A: Biological Sciences and Medical …, 2004 | 125 | 2004 |
| Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle Y Konokhova, S Spendiff, RT Jagoe, S Aare, S Kapchinsky, NJ MacMillan, ... Skeletal muscle 6, 1-16, 2016 | 122 | 2016 |
| Quantitating the capillary supply and the response to resistance training in older men RT Hepple, SLM Mackinnon, SG Thomas, JM Goodman, MJ Plyley Pflügers Archiv 433, 238-244, 1996 | 122 | 1996 |
