Manuela Baccarini
Manuela Baccarini
Professor of Cell Signaling, University of Vienna
Verified email at
TitleCited byYear
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
M Karaghiosoff, R Steinborn, P Kovarik, G Kriegshäuser, M Baccarini, ...
Nature immunology 4 (5), 471, 2003
Embryonic lethality and fetal liver apoptosis in mice lacking the c‐raf‐1 gene
M Mikula, M Schreiber, Z Husak, L Kucerova, J Rüth, R Wieser, ...
The EMBO journal 20 (8), 1952-1962, 2001
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
D Matallanas, D Romano, K Yee, K Meissl, L Kucerova, D Piazzolla, ...
Molecular cell 27 (6), 962-975, 2007
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
E O'Neill, L Rushworth, M Baccarini, W Kolch
Science 306 (5705), 2267-2270, 2004
Raf-1-associated protein phosphatase 2A as a positive regulator of kinase activation
D Abraham, K Podar, M Pacher, M Kubicek, N Welzel, BA Hemmings, ...
Journal of Biological Chemistry 275 (29), 22300-22304, 2000
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer
S Eser, N Reiff, M Messer, B Seidler, K Gottschalk, M Dobler, M Hieber, ...
Cancer cell 23 (3), 406-420, 2013
Ras-dependent and-independent pathways target the mitogen-activated protein kinase network in macrophages.
D Büscher, RA Hipskind, S Krautwald, T Reimann, M Baccarini
Molecular and cellular biology 15 (1), 466-475, 1995
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma
RB Blasco, S Francoz, D Santamaría, M Cañamero, P Dubus, J Charron, ...
Cancer cell 19 (5), 652-663, 2011
Raf-1 regulates Rho signaling and cell migration
K Ehrenreiter, D Piazzolla, V Velamoor, I Sobczak, JV Small, J Takeda, ...
J Cell Biol 168 (6), 955-964, 2005
Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis
V Jesenberger, KJ Procyk, J Yuan, S Reipert, M Baccarini
Journal of Experimental Medicine 192 (7), 1035-1046, 2000
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis
O Yamaguchi, T Watanabe, K Nishida, K Kashiwase, Y Higuchi, T Takeda, ...
The Journal of clinical investigation 114 (7), 937-943, 2004
Growth Phase-Regulated Induction ofSalmonella-Induced Macrophage Apoptosis Correlates with Transient Expression of SPI-1 Genes
U Lundberg, U Vinatzer, D Berdnik, A von Gabain, M Baccarini
Journal of bacteriology 181 (11), 3433-3437, 1999
Raf kinases in cancer–roles and therapeutic opportunities
G Maurer, B Tarkowski, M Baccarini
Oncogene 30 (32), 3477, 2011
Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes.
T Reimann, D Büscher, RA Hipskind, S Krautwald, ML Lohmann-Matthes, ...
The Journal of Immunology 153 (12), 5740-5749, 1994
A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal
F Catalanotti, G Reyes, V Jesenberger, G Galabova-Kovacs, ...
Nature structural & molecular biology 16 (3), 294, 2009
Second nature: biological functions of the Raf‐1 “kinase”
M Baccarini
FEBS letters 579 (15), 3271-3277, 2005
Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo.
RA Hipskind, M Baccarini, A Nordheim
Molecular and Cellular Biology 14 (9), 6219-6231, 1994
Host factor I, Hfq, binds to Escherichia coli ompA mRNA in a growth rate-dependent fashion and regulates its stability
O Vytvytska, JS Jakobsen, G Balcunaite, JS Andersen, M Baccarini, ...
Proceedings of the National Academy of Sciences 95 (24), 14118-14123, 1998
Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and β1 integrin co-signaling
D Telci, Z Wang, X Li, EAM Verderio, MJ Humphries, M Baccarini, ...
Journal of biological chemistry 283 (30), 20937-20947, 2008
Dephosphorylation of Ser-259 regulates Raf-1 membrane association
M Kubicek, M Pacher, D Abraham, K Podar, M Eulitz, M Baccarini
Journal of Biological Chemistry 277 (10), 7913-7919, 2002
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