| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10704 | 2021 |
| TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis J Sreedharan, IP Blair, VB Tripathi, X Hu, C Vance, B Rogelj, S Ackerley, ... Science 319 (5870), 1668-1672, 2008 | 2976 | 2008 |
| Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 2965 | 2009 |
| Endoplasmic reticulum stress signalling–from basic mechanisms to clinical applications A Almanza, A Carlesso, C Chintha, S Creedican, D Doultsinos, B Leuzzi, ... The FEBS journal 286 (2), 241-278, 2019 | 715 | 2019 |
| Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1268-1283. e6, 2018 | 576 | 2018 |
| A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia M Morita, A Al-Chalabi, PM Andersen, B Hosler, P Sapp, E Englund, ... Neurology 66 (6), 839-844, 2006 | 459 | 2006 |
| Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS BN Smith, N Ticozzi, C Fallini, AS Gkazi, S Topp, KP Kenna, EL Scotter, ... Neuron 84 (2), 324-331, 2014 | 411 | 2014 |
| Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase J Mitchell, P Paul, HJ Chen, A Morris, M Payling, M Falchi, J Habgood, ... Proceedings of the National Academy of Sciences 107 (16), 7556-7561, 2010 | 298 | 2010 |
| NEK1 variants confer susceptibility to amyotrophic lateral sclerosis KP Kenna, PTC Van Doormaal, AM Dekker, N Ticozzi, BJ Kenna, ... Nature genetics 48 (9), 1037-1042, 2016 | 282 | 2016 |
| Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector MJD Wagstaff, Y Collaço-Moraes, J Smith, JS de Belleroche, RS Coffin, ... Journal of Biological Chemistry 274 (8), 5061-5069, 1999 | 268 | 1999 |
| The C9ORF72 expansion mutation is a common cause of ALS+/− FTD in Europe and has a single founder BN Smith, S Newhouse, A Shatunov, C Vance, S Topp, L Johnson, ... European Journal of Human Genetics 21 (1), 102-108, 2013 | 254 | 2013 |
| Metabolism of beds of mammalian cortical synaptosomes: response to depolarizing influences JS De Belleroche, HF Bradford Journal of neurochemistry 19 (3), 585-602, 1972 | 254 | 1972 |
| Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays A Malaspina, N Kaushik, J De Belleroche Journal of neurochemistry 77 (1), 132-145, 2001 | 251 | 2001 |
| Cyclooxygenase‐2 induction in cerebral cortex: an intracellular response to synaptic excitation J Adams, Y Collaço‐Moraes, J De Belleroche Journal of neurochemistry 66 (1), 6-13, 1996 | 242 | 1996 |
| Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function PR Maycox, F Kelly, A Taylor, S Bates, J Reid, R Logendra, MR Barnes, ... Molecular psychiatry 14 (12), 1083-1094, 2009 | 225 | 2009 |
| CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia KL Williams, S Topp, S Yang, B Smith, JA Fifita, ST Warraich, KY Zhang, ... Nature communications 7 (1), 11253, 2016 | 219 | 2016 |
| Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis HJ Chen, G Anagnostou, A Chai, J Withers, A Morris, J Adhikaree, ... Journal of Biological Chemistry 285 (51), 40266-40281, 2010 | 208 | 2010 |
| The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death MT Akbar, AMC Lundberg, K Liu, S Vidyadaran, KE Wells, H Dolatshad, ... Journal of Biological Chemistry 278 (22), 19956-19965, 2003 | 197 | 2003 |
| Identification of PEX7 as the second gene involved in Refsum disease DM Van Den Brink, P Brites, J Haasjes, AS Wierzbicki, J Mitchell, ... The American Journal of Human Genetics 72 (2), 471-477, 2003 | 193 | 2003 |
| Biochemical evidence for the presence of presynaptic receptors on dopaminergic nerve terminals J De Belleroche, HF Bradford Brain research 142 (1), 53-68, 1978 | 186 | 1978 |
