| Functional selectivity and classical concepts of quantitative pharmacology JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007 | 1331 | 2007 |
| Activation and allosteric modulation of a muscarinic acetylcholine receptor AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ... Nature 504 (7478), 101-106, 2013 | 990 | 2013 |
| International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors DR Poyner, PM Sexton, I Marshall, DM Smith, R Quirion, W Born, R Muff, ... Pharmacological reviews 54 (2), 233-246, 2002 | 985 | 2002 |
| Allosteric modulation of G protein–coupled receptors LT May, K Leach, PM Sexton, A Christopoulos Annu. Rev. Pharmacol. Toxicol. 47 (1), 1-51, 2007 | 826 | 2007 |
| Mechanisms of signalling and biased agonism in G protein-coupled receptors D Wootten, A Christopoulos, M Marti-Solano, MM Babu, PM Sexton Nature reviews Molecular cell biology 19 (10), 638-653, 2018 | 663 | 2018 |
| Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization. GC Nicholson, JM Moseley, PM Sexton, FA Mendelsohn, TJ Martin The Journal of clinical investigation 78 (2), 355-360, 1986 | 587 | 1986 |
| Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product G Christopoulos, KJ Perry, M Morfis, N Tilakaratne, Y Gao, NJ Fraser, ... Molecular pharmacology 56 (1), 235-242, 1999 | 563 | 1999 |
| G-protein–coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor E Kostenis, G Milligan, A Christopoulos, CF Sanchez-Ferrer, ... Circulation 111 (14), 1806-1813, 2005 | 551 | 2005 |
| Emerging paradigms in GPCR allostery: implications for drug discovery D Wootten, A Christopoulos, PM Sexton Nature reviews Drug discovery 12 (8), 630-644, 2013 | 536 | 2013 |
| Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 506 | 2017 |
| Muscarinic acetylcholine receptors: novel opportunities for drug development AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess Nature reviews Drug discovery 13 (7), 549-560, 2014 | 464 | 2014 |
| Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ... Nature 503 (7475), 295-299, 2013 | 457 | 2013 |
| Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology K Leach, PM Sexton, A Christopoulos Trends in pharmacological sciences 28 (8), 382-389, 2007 | 396 | 2007 |
| Crystal structures of the M1 and M4 muscarinic acetylcholine receptors DM Thal, B Sun, D Feng, V Nawaratne, K Leach, CC Felder, MG Bures, ... Nature 531 (7594), 335, 2016 | 360 | 2016 |
| Novel receptor partners and function of receptor activity-modifying proteins A Christopoulos, G Christopoulos, M Morfis, M Udawela, M Laburthe, ... Journal of Biological Chemistry 278 (5), 3293-3297, 2003 | 356 | 2003 |
| Glucagon-like peptide-1 and its class BG protein–coupled receptors: a long march to therapeutic successes C De Graaf, D Donnelly, D Wootten, J Lau, PM Sexton, LJ Miller, JM Ahn, ... Pharmacological reviews 68 (4), 954-1013, 2016 | 348 | 2016 |
| The role of kinetic context in apparent biased agonism at GPCRs C Klein Herenbrink, DA Sykes, P Donthamsetti, M Canals, T Coudrat, ... Nature communications 7 (1), 10842, 2016 | 347 | 2016 |
| Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 339 | 2018 |
| Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 318 | 2018 |
| In vitro autoradiographic localization of amylin binding sites in rat brain PM Sexton, G Paxinos, MA Kenney, PJ Wookey, K Beaumont Neuroscience 62 (2), 553-567, 1994 | 317 | 1994 |
Denise WoottenMonash Institute of Pharmaceutical SciencesVerified email at monash.edu
