Background Pilot trials suggest that the intracoronary administration of autologous
progenitor cells may improve left ventricular function after acute myocardial infarction.
Methods In a multicenter trial, we randomly assigned 204 patients with acute myocardial …

ContextExercise training in patients with chronic heart failure improves work capacity by
enhancing endothelial function and skeletal muscle aerobic metabolism, but effects on
central hemodynamic function are not well established. ObjectiveTo evaluate the effects of …

Aims To investigate the clinical outcome after intracoronary administration of autologous
progenitor cells in patients with acute myocardial infarction (AMI). Methods and results Using
a double-blind, placebo-controlled multicentre trial design, we randomized 204 patients with …

Objectives The aim of this study was to assess the effects of regular physical exercise on
local inflammatory parameters in the skeletal muscle of patients with chronic heart failure
(CHF). Background Inflammatory activation with increased serum cytokine levels and …

Objectives. The present study was designed to evaluate the effects of an ambulatory training
program in patients with chronic heart failure (CHF) on the ultrastructural morphology of
mitochondria and fiber type distribution of skeletal muscle and its relation to peripheral …

Background—The aim of this study was to investigate the clinical outcome 2 years after
intracoronary administration of autologous progenitor cells in patients with acute myocardial
infarction (AMI). Methods and Results—Using a double-blind, placebo-controlled …

OBJECTIVES The purpose of the study was to investigate if apoptosis occurs in skeletal
muscle myocytes and its relation to exercise intolerance in patients with chronic heart failure
(CHF). BACKGROUND Intrinsic abnormalities of skeletal muscle frequently limit exercise …

Objectives. This study was designed to analyze the effect of iNOS on mitochondrial creatine
kinase (mi-CK) expression and exercise capacity in chronic heart failure (CHF). Background.
The molecular mechanisms underlying exercise intolerance in CHF are still unclear …

Objectives We sought to assess the role of insulin-like growth factor-I (IGF-I) in muscle
wasting in chronic heart failure (CHF), serum concentrations and local muscular IGF-I
expression were determined in patients with severe CHF. Background Chronic heart failure …