Understanding the neuropathology of multiple sclerosis (MS) is essential for improved
therapies. Therefore, identification of targets specific to pathological types of MS may have
therapeutic benefits. Here we identify, by laser-capture microdissection and proteomics …

Communication of science to the general public is increasingly recognized as a
responsibility of scientists (Greenwood, 2001; Leshner, 2003), yet how do scientists learn
these skills? While scientists are thoroughly trained in research methodologies, analytical …

We developed a new, silicon-based peptide array for a broad range of biological
applications, including potential development as a real-time point-of-care platform. We used
photolithography on silicon wafers to synthesize microarrays (Intel arrays) that contained …

This paper describes the Seventh Data Release of the Sloan Digital Sky Survey (SDSS),
marking the completion of the original goals of the SDSS and the end of the phase known as
SDSS-II. It includes 11,663 deg 2 of imaging data, with most of the~ 2000 deg 2 increment …

Autoantibodies against cytokines, chemokines, and growth factors inhibit normal immunity
and are implicated in inflammatory autoimmune disease and diseases of immune
deficiency. In an effort to evaluate serum from autoimmune and immunodeficient patients for …

Macrophages are a diverse population of phagocytic cells that reside in tissues throughout
the body. At sites of infection, macrophages encounter and engulf invading microbes.
Accordingly, macrophages possess specialized effector functions to kill or coordinate the …

Most scientists agree that comprehension of primary scientific papers and communication of
scientific concepts are two of the most important skills that we can teach, but few
undergraduate biology courses make these explicit course goals. We designed an …

Abstract The Sloan Digital Sky Survey (SDSS) started a new phase in 2008 August, with
new instrumentation and new surveys focused on Galactic structure and chemical evolution,
measurements of the baryon oscillation feature in the clustering of galaxies and the quasar …

Abstract The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the
scale of baryon acoustic oscillations (BAO) in the clustering of matter over a larger volume
than the combined efforts of all previous spectroscopic surveys of large-scale structure …

Colorectal cancer (CRC) is the most common tumour type in both sexes combined in
Western countries. Although screening programmes including the implementation of faecal
occult blood test and colonoscopy might be able to reduce mortality by removing precursor …