Mammalian pre-implantation development is a complex process involving dramatic changes
in the transcriptional architecture 1, 2, 3, 4. We report here a comprehensive analysis of
transcriptome dynamics from oocyte to morula in both human and mouse embryos, using …

The large ribosomal subunit catalyses the reaction between the α-amino group of the
aminoacyl-tRNA bound to the A site and the ester carbon of the peptidyl-tRNA bound to the
P site 1, while preventing the nucleophilic attack of water on the ester, which would lead to …

Peptide bond formation is catalyzed at the peptidyl transferase center (PTC) of the large
ribosomal subunit. Crystal structures of the large ribosomal subunit of Haloarcula
marismortui (Hma) complexed with several analogs that represent either the substrates or …

Staggered price-setting and staggered wage-setting are commonly viewed as similar
mechanisms in generating persistent real effects of monetary shocks. In this paper, we
distinguish the two mechanisms in a dynamic stochastic general equilibrium framework. We …

Nanometallic optical antennas are rapidly gaining popularity in applications that require
exquisite control over light concentration and emission processes. The search is on for high-
performance antennas that offer facile integration on chips. Here we demonstrate a new …

The miniaturization of electronic and photonic device technologies has facilitated
information processing and transport at ever-increasing speeds and decreasing power
levels. Nanometallics or 'plasmonics' has empowered us to break the diffraction limit and …

High temperature solid oxide fuel cell (SOFC) technology is a promising power generation
option that features high electrical efficiency and low emissions of environmentally polluting
gases such as CO2, NOox and SOx. It is ideal for distributed stationary power generation …

Realization of a solid oxide fuel cell (SOFC) operating at 700° C on a hydrocarbon fuel or
gaseous H 2 is an outstanding technical target. For the past 25 years, efforts to achieve this
goal have been based on yttria-stabilized zirconia as the electrolyte, a NiO+ electrolyte …

The cyclical behavior of real wages has evolved from mildly countercyclical during the
interwar period to modestly procyclical in the postwar era. This paper presents a general-
equilibrium business-cycle model that helps explain the evolution. In the model, changes in …

In an economy with nominal rigidities in both an intermediate good sector and a finished
good sector, and thus with a natural distinction between CPI and PPI inflation rates, a
benevolent central bank faces a tradeoff between stabilizing the two measures of inflation, a …