Protein surface hydration is fundamental to its structure and activity. We report here the
direct mapping of global hydration dynamics around a protein in its native and molten
globular states, using a tryptophan scan by site-specific mutations. With 16 tryptophan …

A DSP-based improved maximum power point tracking (MPPT) approach for multiple solar
array application is presented. It incorporates a “shared bus” current sharing method that
can regulate many paralleled current mode DC/DC converters. The modular architecture …

Processivity, the ability of single molecules to move continuously along a track, is a
fundamental requirement of cargo-transporting molecular motors. Here, we investigate how
cytoplasmic dynein, a homodimeric, microtubule-based motor, achieves processive motion …

Water motion at protein surfaces is fundamental to protein structure, stability, dynamics, and
function. By using intrinsic tryptophans as local optical probes, and with femtosecond
resolution, it is possible to probe surface-water motions in the hydration layer. Here, we …

Human serum albumin, the most abundant protein found in blood plasma, transports a great
variety of ligands in the circulatory system and undergoes reversible conformational
transitions over a wide range of pH values. We report here our systematic studies of …

A novel power factor correction (PFC) cell, called flyboost, is presented. The proposed PFC
cell combines power conversion characteristics of conventional flyback and boost
converters. Based on the flyboost PFC cell, a new family of single-stage (S/sup 2/) ac/dc …

We report here a complete study of solvation dynamics of tryptophan in bulk water with
femtosecond resolution and present an accurate method for the construction of its solvation
correlation function. The water dynamics was observed in one hundred picosecond (∼ 108 …

We report our systematic examination of tryptophan fluorescence dynamics in proteins with
femtosecond resolution. Distinct patterns of femtosecond-resolved fluorescence transients
from the blue to the red side of emission have been characterized to distinguish local …

A method includes simultaneously driving a load via first and second magnetically coupled
regulator phases for a first duration, uncoupling one of the phases from the load after the first
duration, and, after uncoupling the one phase from the load, allowing a current through the …

The kinesin-8 family of microtubule motors plays a critical role in microtubule length control
in cells. These motors have complex effects on microtubule dynamics: they destabilize
growing microtubules yet stabilize shrinking microtubules. The budding yeast kinesin-8 …