Mammalian pre-implantation development is a complex process involving dramatic changes
in the transcriptional architecture 1, 2, 3, 4. We report here a comprehensive analysis of
transcriptome dynamics from oocyte to morula in both human and mouse embryos, using …

Hexaploid wheat (Triticum aestivum) is a globally important crop. Heat, drought and their
combination dramatically reduce wheat yield and quality, but the molecular mechanisms
underlying wheat tolerance to extreme environments, especially stress combination, are …

Twenty-four male Kazak sheep and 30 Xinjiang fine wool sheep at different ages were
selected to investigate the development-dependent expression levels of fatty acid synthase
(FAS) gene and hormone-sensitive lipase (HSL) gene in muscle and their effects on the …

Abstract The Deleted in Azoospermia (DAZ) genes encode potential RNA-binding proteins
that are expressed exclusively in the germ-line. The bovine Deleted in Azoospermia-like
gene is a strong candidate for male cattle-yak infertility. In this work, with the goe goal to …

Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to
human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study,
we analyzed DNA methylation patterns in a large number of hiPSCs (n= 114) and hESCs …

The purpose of the present work is to understand the evolution of microstructure and
microchemistry during homogenization of the Al–Mg–Mn alloy AA 5454 (Al Mg3 Mn). It has
previously been shown that a two-stage homogenization practice may alter the particles …

At present, the Tibetan Mastiff is the oldest and most ferocious dog in the world. However,
the origin of the Tibetan Mastiff and its phylogenetic relationship with other large breed dogs
such as Saint Bernard are unclear. In this study, the primers were designed according to the …

Retinal pigment epithelium (RPE) cells can be obtained through in vitro differentiation of
both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). We have
previously identified 87 signature genes relevant to RPE cell differentiation and function …

The DAZL gene plays an important role in gametogenesis. Microdeletion and mutation of
this gene has been frequently associated with the sterility in both vertebrates and
invertebrates. Here, a cDNA containing the complete open reading frame of DAZL gene …

To improve the knowledge about the biogeographic patterns of bacteria in soils
contaminated with crude oil, we studied the effects of local geochemical properties and
geographic distance on bacterial community structure in oil contaminated soil in five oil …