| The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease NM El-Sayed, PJ Myler, DC Bartholomeu, D Nilsson, G Aggarwal, ... Science 309 (5733), 409-415, 2005 | 1804 | 2005 |
| The Genome of the Kinetoplastid Parasite, Leishmania major AC Ivens, CS Peacock, EA Worthey, L Murphy, G Aggarwal, M Berriman, ... Science 309 (5733), 436-442, 2005 | 1756 | 2005 |
| A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes SR Wilkinson, MC Taylor, D Horn, JM Kelly, I Cheeseman Proceedings of the National Academy of Sciences 105 (13), 5022-5027, 2008 | 527 | 2008 |
| High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome S Alsford, DJ Turner, SO Obado, A Sanchez-Flores, L Glover, M Berriman, ... Genome research 21 (6), 915-924, 2011 | 518 | 2011 |
| Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need MC Field, D Horn, AH Fairlamb, MAJ Ferguson, DW Gray, KD Read, ... Nature Reviews Microbiology 15 (4), 217-231, 2017 | 422 | 2017 |
| Antigenic variation in African trypanosomes D Horn Molecular and biochemical parasitology 195 (2), 123-129, 2014 | 357 | 2014 |
| High-throughput decoding of antitrypanosomal drug efficacy and resistance S Alsford, S Eckert, N Baker, L Glover, A Sanchez-Flores, KF Leung, ... Nature 482 (7384), 232-236, 2012 | 355 | 2012 |
| Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story N Baker, HP de Koning, P Mäser, D Horn Trends in parasitology 29 (3), 110-118, 2013 | 314 | 2013 |
| Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei BM Mony, P MacGregor, A Ivens, F Rojas, A Cowton, J Young, D Horn, ... Nature 505 (7485), 681-685, 2014 | 220 | 2014 |
| A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei VP Alibu, L Storm, S Haile, C Clayton, D Horn Molecular and biochemical parasitology 139 (1), 75-82, 2005 | 195 | 2005 |
| Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects S Alsford, T Kawahara, L Glover, D Horn Molecular and biochemical parasitology 144 (2), 142-148, 2005 | 191 | 2005 |
| Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes N Baker, L Glover, JC Munday, D Aguinaga Andrés, MP Barrett, ... Proceedings of the National Academy of Sciences 109 (27), 10996-11001, 2012 | 187 | 2012 |
| Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei S Alsford, D Horn Molecular and biochemical parasitology 161 (1), 76-79, 2008 | 167 | 2008 |
| A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei D Horn, GAM Cross Cell 83 (4), 555-561, 1995 | 164 | 1995 |
| Molecular mechanisms underlying the control of antigenic variation in African trypanosomes D Horn, R McCulloch Current opinion in microbiology 13 (6), 700-705, 2010 | 162 | 2010 |
| A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation S Alsford, T Kawahara, C Isamah, D Horn Molecular microbiology 63 (3), 724-736, 2007 | 154 | 2007 |
| RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the African trypanosome SR Wilkinson, D Horn, SR Prathalingam, JM Kelly Journal of Biological Chemistry 278 (34), 31640-31646, 2003 | 145 | 2003 |
| Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of … JC Munday, AA Eze, N Baker, L Glover, C Clucas, D Aguinaga Andrés, ... Journal of Antimicrobial Chemotherapy 69 (3), 651-663, 2014 | 142 | 2014 |
| Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ... Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019 | 141 | 2019 |
| Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 N Baker, S Alsford, D Horn Molecular and biochemical parasitology 176 (1), 55-57, 2011 | 135 | 2011 |
Sam AlsfordLondon School of Hygiene & Tropical MedicineVerified email at lshtm.ac.uk
