| The ancient drug salicylate directly activates AMP-activated protein kinase SA Hawley, MD Fullerton, FA Ross, JD Schertzer, C Chevtzoff, KJ Walker, ... Science 336 (6083), 918-922, 2012 | 815 | 2012 |
| Chaperoned ubiquitylation—crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex M Zhang, M Windheim, SM Roe, M Peggie, P Cohen, C Prodromou, ... Molecular cell 20 (4), 525-538, 2005 | 456 | 2005 |
| Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ: a distinct upstream kinase mediates Ser-172 phosphorylation … K Clark, L Plater, M Peggie, P Cohen Journal of Biological Chemistry 284 (21), 14136-14146, 2009 | 417 | 2009 |
| Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3 JT Murray, DG Campbell, N Morrice, GC Auld, N Shpiro, R Marquez, ... Biochemical Journal 384 (3), 477-488, 2004 | 391 | 2004 |
| Novel cross-talk within the IKK family controls innate immunity K Clark, M Peggie, L Plater, RJ Sorcek, ERR Young, JB Madwed, ... Biochemical journal 434 (1), 93-104, 2011 | 347 | 2011 |
| Control of AMPK-related kinases by USP9X and atypical Lys29/Lys33-linked polyubiquitin chains AK Al-Hakim, A Zagorska, L Chapman, M Deak, M Peggie, DR Alessi Biochemical Journal 411 (2), 249-260, 2008 | 303 | 2008 |
| Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion G Rena, YL Woods, AR Prescott, M Peggie, TG Unterman, MR Williams, ... The EMBO journal 21 (9), 2263-2271, 2002 | 301 | 2002 |
| p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP G Sabio, JSC Arthur, Y Kuma, M Peggie, J Carr, V Murray‐Tait, F Centeno, ... The EMBO journal 24 (6), 1134-1145, 2005 | 292 | 2005 |
| Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages K Clark, KF MacKenzie, K Petkevicius, Y Kristariyanto, J Zhang, HG Choi, ... Proceedings of the National Academy of Sciences 109 (42), 16986-16991, 2012 | 276 | 2012 |
| Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP‐K2 and its interaction with cytokine mRNAs S Rousseau, N Morrice, M Peggie, DG Campbell, M Gaestel, P Cohen The EMBO journal, 2002 | 276 | 2002 |
| Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase RW Hunter, CC Hughey, L Lantier, EI Sundelin, M Peggie, E Zeqiraj, ... Nature medicine 24 (9), 1395-1406, 2018 | 259 | 2018 |
| Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide M Windheim, C Lang, M Peggie, LA Plater, P Cohen Biochemical Journal 404 (2), 179-190, 2007 | 243 | 2007 |
| Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK 1‐dependent phosphorylation and activation A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ... EMBO reports 16 (8), 939-954, 2015 | 226 | 2015 |
| Allosteric regulation of glycogen synthase controls glycogen synthesis in muscle M Bouskila, RW Hunter, AFM Ibrahim, L Delattre, M Peggie, ... Cell metabolism 12 (5), 456-466, 2010 | 225 | 2010 |
| Phosphorylation and 14‐3‐3 binding of Arabidopsis trehalose‐phosphate synthase 5 in response to 2‐deoxyglucose JE Harthill, SEM Meek, N Morrice, MW Peggie, J Borch, BHC Wong, ... The Plant Journal 47 (2), 211-223, 2006 | 200 | 2006 |
| The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1 A Ordureau, H Smith, M Windheim, M Peggie, E Carrick, N Morrice, ... Biochemical journal 409 (1), 43-52, 2008 | 197 | 2008 |
| Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma S Morton, L Hesson, M Peggie, P Cohen FEBS letters 582 (6), 997-1002, 2008 | 195 | 2008 |
| Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ... The EMBO journal 34 (22), 2840-2861, 2015 | 185 | 2015 |
| The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver K Patel, M Foretz, A Marion, DG Campbell, R Gourlay, N Boudaba, ... Nature communications 5 (1), 4535, 2014 | 173 | 2014 |
| Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IκBα kinase M Windheim, M Stafford, M Peggie, P Cohen Molecular and cellular biology 28 (5), 1783-1791, 2008 | 162 | 2008 |
Philip CohenMRC Protein Phosphorylation Unit, University of Dundee ScotlandVerified email at dundee.ac.uk
